摘要
目的:探讨健脾通里中药芪黄煎剂对胃癌手术后胃肠运动功能恢复的影响及其对术后胃肠激素的调节。方法:将30例胃癌患者随机分为研究组和对照组,观察两组术后胃肠动力恢复时限变化(肠鸣音的恢复、通气时限、首次排便时间)和胃肠激素的变化(胃动素、血管活性肠肽、生长抑素)。结果:研究组胃肠动力恢复时限(肠鸣音的恢复、通气时限、首次排便时间)均较对照组明显缩短(P<0.01～0.05)。术后7d胃动素水平均明显回升,两组相比,术后应用中药芪黄煎剂能有效调节术后血管活性肠肽、生长抑素的变化(P<0.05)。结论:胃癌手术后早期应用健脾通里中药有利于术后胃肠运动功能恢复,中药芪黄煎剂能调节胃肠激素水平,使之在手术后尽快恢复正常。
Objective To observe the influence of medicinal herbs Qihuang（芪黄） decoction on the recovery of gastrointestinal peristalsis and to investigate the regulation of gastrointestinal hormones after gastric cancer operation. Methods Thirty cases underwent gastric cancer operation were divided into study group and control group randomly. Changes of gastrointestinal peristalsis recovery time （recovery of intestinal gurgling sound, first ventilation, first defaecation time） and gastrointestinal hormones, motilin（MOT）, vasoactive intestinal peptide（VIP）, somatostatin（SS） levels after operation were observed in both groups. Results The time needed for gastrointestinal peristalsis recovery was significantly shorter in the study group than in the control group （ P 〈 0.01 - 0.05）. The level of MOT significantly increased on 7d after operation. Compared with the control group, the use of herbs after operation might effectively modulate the changes of VIP and SS after operation （ P 〈 0.05 ） . Conclusion The early use of Jianpi tongli （健脾通里 ） Qihuang decoction herbs after gastric cancer operation is bene-ficial for the recovery of gastrointestinal peristalsis after operation, the decoction may regulate the levels of MOT, VIP and SS, and enhance the recovery of gastrointestinal hormone function after operation.
出处
《中国中西医结合外科杂志》
CAS
2008年第6期538-541,共4页
Chinese Journal of Surgery of Integrated Traditional and Western Medicine
关键词
胃癌
芪黄煎剂
胃肠动力
胃肠激素
gastric cancer, Qihuang decoction, gastrointestinal peristalsis, gastrointestinal hormone
