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健康人运动试验时血浆心钠素水平的变化 被引量:1

The Change of Atrial Natriuretic Factor during Exercise in Healthy Man
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摘要 用放射免疫测定方法和心导管监测了10名健康成人卧位踏车试验时心钠素和血流动力学的变化。运动中血浆心钠素浓度升高(P<0.01),并与平均肺动脉压和肺毛细血管嵌顿压相关(P<0.01)。提示运动时心钠素浓度变化与肺动脉压和肺毛细血管嵌顿压变化有关,提示运动试验可望做为一种评价心脏内分泌功能的方法之一。 The plasma concentration of atrial natriuretic factor (ANF) and hemody-namics were measured in ten healthy men by specific radio-immunoassy and cardiac catheterization on supine bicycle exercise test. The plasma ANF level significantly increased during exercise than that of resting state (p<0.01) . The increase of concentration of plasma ANF during exercise were significantly correlated with the increse of mean pulmonary artery pressure and pulmonary capillary wedge pressure (p<0.01) . These findings indicated that the concentration of plasma ANF were in response to the increases of pulmonary artery pressure and pulmonary capillary wedge pressure during exercise, and suggested that exercise may act as a test to evaluate the endocrine function of the heart.
出处 《基础医学与临床》 CSCD 1990年第5期40-43,共4页 Basic and Clinical Medicine
关键词 必钠素 血流动动力学 心导管 atrial natriuretic factor hemodynamics cardiac catheterization
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  • 1K. Nakao,A. Sugawara,N. Morii,M. Sakamoto,T. Yamada,H. Itoh,S. Shiono,Y. Saito,K. Nishimura,T. Ban,K. Kangawa,H. Matsuo,H. Imura. The pharmacokinetics ofα-human atrial natriuretic polypeptide in healthy subjects[J] 1986,European Journal of Clinical Pharmacology(1):101~103 被引量:1

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