摘要
目的介绍一种治疗痛性神经瘤的新方法和初步临床疗效。方法2002年～2006年，应用阿霉素神经干注射联合神经瘤切除或松解治疗痛性神经瘤患者9例。其中8例切除残端神经瘤后，将神经近端置于正常的软组织内；1例连续性神经瘤仅做神经松解。所有病例均在神经瘤切除或松解后，根据神经干粗细的不同分别用1％的阿霉素0．3～1．0ml作近端神经干注射。结果经过24—60个月的临床随访，7例残端神经瘤患者的疼痛明显缓解，1例疼痛减轻，1例无效（仅做神经松解），手术优良率为77．8％。结论阿霉素神经干注射联合神经瘤切除能有效缓解残端神经痛。
Objective To introduce a novel method to treat painful neuroma and evaluate the preliminary chnical outcomes. Methods From 2002 to 2006, 9 patients with painful neuromas were treated. The surgical technique included neuroma resection and embedding of the proximal nerve end into adjacent normal soft tissue in 8 patients and neurelysis in 1 patient. According to the size of the nerve, 0.3 to 1.0 ml of 1% adriblastine was injected into the proximal nerve stump. Results The mean follow-up was 34 months （range, 24 to 60 months）. Seven of the 9 patients experienced complete and permanent pain relief. Some mild degree of pain returned in 1 patient. Postoperative pain level was not changed for the patient who underwent neurelysis and intraneural adriblastine injection. The overall effective rate was 77. 8%. Conclusion Stump pain caused by painful neuroma can be effectively treated by neuroma resection and intraneural adriblastine injection .
出处
《中华手外科杂志》
CSCD
北大核心
2008年第6期329-331,共3页
Chinese Journal of Hand Surgery
基金
卫生部临床学科重点基金资助项目（2007-66）
上海市周围神经显微外科重点实验室课题基金资助项目（05DE22108）
关键词
周围神经
神经瘤
疼痛
外科手术
阿霉素
Peripheral nerve
Neuroma
Pain
Surgical procedures,operative
Adriblastine
