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容量复苏对早期严重创伤性休克患者血流动力学和氧输送的影响

Effect of fluid resuscitation on hemodynamics and oxygen in severe trauma patients
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摘要 目的探讨大容量复苏对早期严重创伤性休克患者血流动力学和氧输送的影响。方法监测24例严重腹部创伤患者不同容量复苏时的血流动力学和氧代谢指标。结果容量复苏收缩压从80~901/mmHg(1mmHg=0.133kPa)上升到100-120mmHg时,平均复苏容量分别为(2286±521)ml(1h)和(34864-758)ml(2h)。心脏指数(CI)从(2.0±0.5)L/(min·m^2)上升为(3.24±0.6)L/(min·m^2)(P〈0.05),体循环阻力指数(SVRI)从(1857.6±750.2)dyn·s/(cm^5·m^2)上升为(3741.5±862.1)dvn·s/(cm^5·m^2)(P〈0.05),与之相对应,氧输送指数(D02)从(301.1±74.1)ml/(min ·m^2)升为(554.1±80.0)ml/(min·m^2)(P〈0.05),氧耗指数(VO2)为(99.74±51.4)ml/(min·m^2)升为(147.2±60.1)ml/(min·m^2)(P〈0.05),氧摄取指数(O2ext)为(33.1±9.1)%下降至(26.64±8.0)%(P〈0.05)。结论在急诊抢救中,早期大容量复苏能改善血流动力学和氧代谢。 Objective To observe the effect of fluid resuscitation on hemodynamics and oxygen in severe trauma patients. Methods Parameters of hemodynamic and oxygen metabolism in different fluid volume resuscitation in 24 severe trauma patients who were injured on abdominal were measured. Results By fluid resuscitation, as the systolic blood pressure was raised from 80 -90 mm Hg( 1 mm Hg =0. 133 kPa) to 100 - 120 mm Hg,cardiac index rose from ( 2.0 ±0. 5 ) L/( min · m^2 ) to ( 3.2 ± 0.6 )L/( min · m^2 ) ( P 〈 0.05 ), systemic vascular resistance index rose from ( 1857.6± 750.2 dyn ·s/( cm^5 · m^2 ) to ( 3741.5 ± 862.1 ) dyn · s/( cm^5 · m^2 ) significantly ( P 〈 0.05 ). Meanwhile,oxygen delivery index rose from ( 301. 1 ± 74. 1 ) ml/( min · m^2) to ( 554. 1± 80.0 ) mE/( min · m^2 ) ( P 〈0.05 ) ,and oxygen consumption index also rose (99.7 ± 51.4 ) ml/( min · m^2 ) to ( 147.2 ± 60.1 ) ml/( min · m^2 ) remarkably ( P 〈 0.05 ) , the rate of oxygen expenditure decreased from 133.1 ± 9.1 ) % to ( 26.6 ± 8.0 ) % significantly ( P 〈 0. 05 ). Conclusion Large volume resuscitation maybe benefit to the improvement of hemodynamics and oxygen metabolism in the emergency resuscitation.
出处 《中国综合临床》 北大核心 2008年第12期1272-1274,共3页 Clinical Medicine of China
关键词 创伤性休克 容量复苏 血流动力学 氧输送 Traumatic shock Fluid resuscitation Hemodynamics Oxygen delivery
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