摘要
目的回顾分析神经外科颅脑手术后发生颅内感染的危险因素,为临床预防和控制颅内感染提供依据。方法对2006年1—8月神经外科颅脑手术后38例发生颅内感染和68例未发生颅内感染病例的一般资料、基础疾病、主要诊断、手术情况、抗菌药物应用情况、侵入性操作、住院时间及手术人员等因素进行统计分析。结果单因素分析结果显示,两组病例在主要诊断、手术入路方式、入住重症监护室、手术持续时间、住院时间、留置导尿、H2受体阻滞剂(包括质子泵抑制剂)应用、手术人员等方面有统计学差异(均P<0.05);进一步通过多因素Logistic回归分析发现,手术持续时间和手术人员是颅脑手术后发生颅内感染的独立危险因素。结论颅脑手术后发生颅内感染与手术持续时间和手术人员的手术技巧及其无菌观念有关。
Objective To study the risk factors for post-craniotomy intracranial infection in patients in department of neurosurgery, and provide reference for the prevention and control of intracranial infection. Methods Thirty-eight patients with intracranial infection and 68 patients without intracranial infection from January to August 2006 were investigated through case-control study of patients＇ general information, basic diseases, main diagnosis, operation, antimicrobial use, invasive procedure, length of hospitalization and operation medical personnel etc. Results Univariate regression analysis showed there were significant difference in main diagnoses of patients, the craniotomy method, staying in ICU, duration of operation, length of hospitalization, indwelling ureter, use of H2 receptor antagonists （including proton pump inhibitor） and operation medical personnel between two groups （P〈0. 05） ; multivariate Logistic regression analysis showed that duration of operation and operation medical personnel were independent factors for post-craniotomy intracranial infection. Conclusion Post-craniotomy intracranial infection in patients is related with duration of operation, operation skill and sterile awareness of operation medical personnel.
出处
《中国感染控制杂志》
CAS
2008年第6期396-398,共3页
Chinese Journal of Infection Control
关键词
神经外科
开颅手术
医院感染
颅内感染
危险因素
病例对照研究
department of neurosurgery
craniotomy
nosocomial infection
intraeranial infection
risk factors
case control study
