摘要
目的探讨胸水和血清中腺苷脱氨酶(ADA)、癌胚抗原(CEA)、乳酸脱氢酶(LDH)、结核抗体(TB-Ab)和糖抗原199(CA199)对结核性胸水和癌性胸水的鉴别诊断。方法检测经确诊的患者的胸水和血清中ADA、CEA、LDH、TB-Ab和CA199的含量。结果CEA、LDH、CA199诊断癌性胸水的敏感性分别是75.6%、75.6%、73.1%;特异性是88.0%、89.3%、90.7%。ADA、TB-Ab诊断结核性胸水的敏感性分别是73.3%、62.67%;特异性是90.2%、90.2%。五项联合检测其敏感性是78.0%,特异性是93.3%。结论ADA、CEA、LDH、TB-Ab和CA199联合检测对结核性胸水和癌性胸水有较高的鉴别诊断价值。
Objective To investigate the value of combinative detecting the level of ADA,CEA, LDH, TB-Ab and CA199 in tuberculous and malignant pleural effusion. Methods To determine the levels of ADA, CEA,LDH,TB-Ab and CA199 in pleural effusions and blood serum of the diagnosed patients. Results The sensitivity of CEA, LDH and CA199 respectively is： 75.6% ,75.6% ,73.1% ; veracity is 88.0% ,89.3%, 90.7%. The sensitivity of diagnosing tuberculous pleural effusion by determining the level of ADA and TB-Ab in pleural effusion is 73.3% ,62. 67% ;veracity is 90. 2% ,90. 2%. Combined five detections in pleural effusion, the sensitivity is 78.0%, veracity is 93. 3 %. Conclusion Combined detections of ADA, CEA, LDH, TB-Ab and CA19-9 have high value to differential diagnosis of tuberculous and malignant pleural effusion.
出处
《中国实用医药》
2008年第30期10-11,共2页
China Practical Medicine
