摘要
目的检查有输血史或妊娠史的患者血清(浆)中的不规则抗体,降低或避免溶血性输血反应的发生。方法用微柱凝胶coombsIgG卡对6486例有输血史或妊娠史患者的血标本进行不规则抗体筛查和鉴定,将不规则抗体阳性的标本用coombsIgG卡进行交叉配血。结果不规则抗体阳性24例,阳性率0.37。其中,抗-D3例,抗-E4例,抗-C2例,抗-A11例,抗-M2例,抗-EC2例,抗-Cc1例,抗-JKa2例,抗-JKb1例,抗-FYa2例,抗-Lea1例,非特异性抗体3例。结论不规则抗体筛查能有效降低或避免溶血性输血反应的发生,保证输血安全,对有输血史和妊娠史的患者尤为重要。
Objective To analyze irregular antibodies in the serum samples from patients with a history of blood transfusion or pregnancy for the prevention of hemolytic transfusion reaction. Methods 6 486 blood samples were screened and identified using the Grifols Diagnostic Micro-column IgG Card. Positive samples were cross-matched with Grifols Diagnostic Micro-column IgG Card. Results 24 samples （0.37%） were found positive： 3 cases of anti-D, 4 cases of anti-E, 2 cases of anti-C, 1 case of anti-A1, 2 cases of anti-M, 2 cases of anti-EC, 1 case of anti-Cc, 2 cases of anti-JKa, 1 case of anti-JKb, 2 cases of anti-FYa, 1 case of anti-Lea and 3 cases of non-specificity antibody. Conclusion Screening of irregular antibodies can effectively reduce the incidence of hemolytic transfusion reaction. It is especially important for the patients with a history of blood transfusion or pregnancy.
出处
《热带医学杂志》
CAS
2008年第11期1149-1151,共3页
Journal of Tropical Medicine
