摘要
以2-氯-5-氯甲基噻唑为原料,经过两步反应高产率得到标题化合物,总收率88.9%。
5- Hydroxymethylthiazole, a key intermediate for Ritonavir, was synthesized from 2-chloro-5-chloromethyhhiazole through two steps of reactions, and the product yield reached 88.9 % .
出处
《化学试剂》
CAS
CSCD
北大核心
2008年第11期856-856,870,共2页
Chemical Reagents
