摘要
本文报道了1例女性双侧乳腺癌。在其第二侧腋窝淋巴结发现了转移性化生性癌而双侧乳腺和第一侧腋窝淋巴结均未发现化生性癌。患者的病程经过和肿瘤组织、细胞病理形态的演变以及免疫组化结果均表明间叶肿瘤组织部分是化生而来的。S－100（＋）和actin（＋）显示了肿瘤组织肌上皮细胞源性。肿瘤组织中的破骨细胞样巨细胞，其CD68（＋），显示其来源于正常的组织细胞，是机体对肿瘤的反应。本文还对化生性癌的诊断和鉴别诊断进行了讨论。
A female case of bilateral breast carcinoma is presented. In two axillary nodes of the second side,metastatic metaplastic carcinoma appeared, while in both side breasts and first side axillary nodes there were nometastatic carcinoma components at all. The evolution of the course, morphology and the immunophenotype ofthis lesion indicated that the tumors were derived from myoepithelial cells. The osteoclastic giant cells in the tumortissue expressed CD68, which showed that these cells might have arisen from cells of the macrophage lineage andwere most likely a reactive infiltrate. The criteria of its diagnosis and differentiation from sarcomas were discussed.
出处
《诊断病理学杂志》
CSCD
1997年第2期96-98,共3页
Chinese Journal of Diagnostic Pathology
关键词
双侧
乳腺癌
化生性癌
诊断
鉴别诊断
Bilateral breast carcinoma Metaplastic carcinoma Myoepithelial cell
