摘要
选用硅橡胶管（ＳＲ）、涤纶纤雏材料（ＰＥＴＦ）、聚氯乙烯管（ＰＶＣ）及用醋酸纤维素（ＣＡ）、聚醚砜（ＰＥＳ）、聚氨酯（Ｐｕ）涂层的聚氯乙烯管，分别与血清在３７℃下进行循环接触，根据接触前（０ｍｉｎ）、接触后５、１５．６０、１８０ｍｉｎ取血清，用ＩＬ－Ｍｏｎａｒｃｈ７６１型生化分析仪测定Ｃ３、Ｃ４，用试管法测定ＣＨ＿（５０）。实验结果表明，ＣＡ、ＰＥＴ、ＳＲ材料接触后血清的Ｃ３、Ｃ４、ＣＨ＿（５０）明显低于接触前，其中ＣＡ接触后１８０ｍｉｎ的血清ＣＨ＿（５０）明显低于接触前及接触后５．１５．６０ｍｉｎ的ＣＨ＿（５０）值。其它材料实验前后比无明显差异。
The Silicon rubber (SR) tube, Polyester fiber (PETF) materials, Polyvinyl chloride (PVC) tube, and PVC tube coated with cellulose acetate (CA), Polyether suffone (PES), Polyurethane (PU) were contacted with circular serum at 37℃. Data before contact after contact for 5, 15, 60, 180min were measured respectively, the CH50 values in serum being assayed with the method of mayer a complement titre, and complement3 (C3) and complement4. (C4) being measured with biochemical analysis instrument (IL-Morarch761). The results showed that concentration of C3, C4, CH50, in serum significantly decreased after contact with CA, PETF; SR, while CH50 value after contact with CA at 180min was significantly lower than those before contact and after contact for 5, 15, 60min. No significant results showed in cases of contact with any other kind of the material.
出处
《北京生物医学工程》
1997年第3期172-177,共6页
Beijing Biomedical Engineering
基金
国家自然科学基金
关键词
生物材料
体外血清接触
CH50
补体
Biomaterial material
Extracoporeal serum contact
CH50
Complement activation
