摘要
目的研究免疫营养对外科脓毒症患者APACHEⅡ评分的影响。方法将40例外科脓毒症患者随机分成研究组和对照组,各20例。研究组为免疫营养组,对照组为常规营养组。两组均给予常规外科治疗,并于术后第1d开始给予静脉营养治疗7d,其中研究组静脉应用谷氨酰胺,比较两组APACHEⅡ评分的变化。结果两组治疗后APACHEⅡ评分均下降,研究组较对照组下降更为明显(P<0.05)。结论谷氨酰胺增强的肠外营养能减轻外科脓毒症患者病情的危重程度,改善预后。
Objective To evaluate the treatment of immunonutrition in patients with severe sepsis.Methods Forty patients with severe sepsis were observed in this study.They were divided into immunonutrition group and control group in randomized controlled clinical trial.All patients were treated with routine surgical treatment combined with parenteral nutrition and were observed for 7 days. 20 cases in immunonutrition group were treated with glutamine and another 20 cases in control group without glutamine,and scores of acute physiology and chronic health evaluation （ APACHE Ⅱ ） were analysed respectively.Results After a week of nutritional support,the score of APACHE Ⅱ decreased significantly in two groups（P〈0.05）, and the decrease in immunonutrition group was more obvious than in control group （P〈0.05）.Conclusion Gin-intensified parenteral nutrition can help to resume the function of cells and organs, and reduces the severity of the sepsis as well as improves the prognosis.
出处
《江西医药》
CAS
2008年第10期1005-1006,共2页
Jiangxi Medical Journal
基金
江西省科技成果重点推广项目(2007)
江西省卫生厅科技计划项目(20071024)
关键词
谷氨酰胺
脓毒症
肠外营养
免疫营养
glutamine
sepsis
parenteral nutrition
immunonutrition
