摘要
目的:了解阻塞型睡眠呼吸暂停综合征(OSAS)患者在自动调节正压呼吸机(auto-CPAP)治疗前后的认知功能变化。方法:用auto-CPAP治疗58例OSAS患者,治疗前、后分别采用多导睡眠分析仪(PSG)及简易精神状态检查法(MMSE)对患者进行检测,分析治疗前、后睡眠结构及认知功能的变化。结果:治疗前患者均有明显的夜间睡眠呼吸紊乱、低氧血症和不同程度的认知功能障碍,治疗6个月后患者临床症状消除,睡眠结构恢复正常,认知功能明显改善(P<0.01)。结论:auto-CPAP治疗不仅使阻塞型睡眠呼吸暂停综合征(OSAS)患者嗜睡、疲乏等临床症状消失,明显改善睡眠结构,而且改善认知功能。
Objective：To evaluate the cognitive function of the patients with obstructive sleep apnea syndrome （OSAS） before and after auto - continuous positive airway pressure （ auto - CPAP） treatment. Methods ： Fifty - eight OSAS patients were treated by auto- CPAP, and evaluated their sleep feature and Cognitive Function by polysomnogram （PSG） and mini -mental state examination （MMSE） before and after treatment. Results ： Before treatment Fifty - eight studies reviewed sleep - related breathing disorders, noc- turnal hypoxemia and cognitive dysfunctions, After 6 monthg treatment, clinical symptoms of the patients were disappeared. And the sleep pattern recovered, the cognitive function improved markedly （P 〈 0.01 ）. Conclusions ： Not only can the treatment of auto - CPAP relief of drowse and fatigue and improve sleep structure of the patients with, but also their cognitive function is improved in OSAS.
出处
《中国民康医学》
2008年第21期2485-2486,2488,共3页
Medical Journal of Chinese People’s Health
关键词
自动调节正压通气
阻塞型睡眠呼吸暂停综合征
认知功能
Auto -continuous positive airway pressure （auto- CPAP）
Obstructive sleep apnea syndrome （OSAS）
Cognitive function
