摘要
１９９３年广西８４个麻疹暴发点的流行病学和血清学调查发现，暴露后１～３月龄、４－５月龄、６～７月龄、８－１１月龄的未接种麻疹疫苗（ＭＶ）儿童的发病率分别为２．５％．１３．０％．１６．３％、１９．７％。血凝抑制抗体阴性率分别为０％、７１．２％．７９．２％．８５．９％。而１一７岁未接种儿童ＭＶ暴露后的发病率为２４．４％。根据所得资料，作者建议ＭＶ免疫可采用两针法，第１针提前到４一６月龄，可降低婴幼儿麻疹发病率，第２针在１５－２３月龄，可弥补因第１针免疫不成功或漏种的易感儿。
The epidemiologic and serologic investigation in 84 outbreaks of measles was conducted in Guangxi , 1993 . It was found that after exposure, the measles attack rate were 2.5%, 13.0%, 16.3% and 19.7%, the HI antibody negative rate were 50%, 71.2%, 79.2%, and85.9% in infants aged 1-3 months, 4-5 months , 6-7 months and 8-1l months respectively. The measles attack rate in children aged 1 - 7 years was 24.4% According to above data, a suggestion is recommended. that two - dose measles vaccination schedule should be performed. The first dose should be given to infants aged 4-6 months, that can decrease the infantile attack rate, the second dose should be given to infants aged 15 - 23 months, that can prevent susceptible children of unsuccessful and missed vaccination in the first dose.
出处
《中国计划免疫》
1997年第1期16-18,共3页
Chinese Journal of Vaccines and Immunization
关键词
麻疹
疫苗
初免月龄
接种针次
infantile measles, Vaccination age and dose .
