摘要
低浓度（0．25％）布比卡因间断硬膜外腔注入，用于开胸术后持续镇痛，观察对心功能的影响，与未用硬股外阻滞组进行比较。结果。两组间术前、术后8h各参数无显著差异（P＞0．05），术后16、24h相差显著（P＜0.05）；未用硬膜外阻滞镇痛组术后8、16、24h各参数与术前比相差显著（P＜0．05），硬膜外阻滞镇痛组与术前比，8h相差显著（P＜0.05），16h部分参数无显著差异（P＞0．05），24h除心率外其它参数天显著差异（P＞0．05）。表明：开胸术后心功能明显下降，24h内不能恢复正常，而术后硬膜外间断注入低浓度布比卡因，用手术后持续镇痛，可使心功能提早至术后16h恢复接近正常，24h除心率外其它参数基本恢复正常，且不干扰呼吸，亦不造成循环功能紊乱。
Fourty petients were included for the study of the influence of postoperative analgesia on the cardiac function in patients undersoing thoracotomy. 0. 25% bupivacaine was intermittently administered into epidural space in analgesia group (n=20) after operation. In control group (n=20), no epidural block but meperidine i. m. was used for postoperative analgesia. Results showed that no stutistical differences in cardiac function was found preoperatively and in the first 8 hours after operation between two groups (P>0.05). However obvious differences were found (P<0.05) in 16~ 24 hours postoperatively. The parameters of cardiac founction chAnged markedly (P<0.05) at 8, 16 and 24 hours postoperatively in control group, comparing to preoperative values. In analgesia group, all parameters changed significantly at 8 hours, some perameters returned to normal range at 16 hours, and all parameters but heart rate were normal at 24 hours petoperatively, comparing to the preoperative values. The results indicated that the cardiac founction did not resume to normal until 24 hours after thoracotomy in control group. The epidural administration of low concentation bupivacaine for postoperative analgesia could help the cardiac function resuming to normal as early as 16 hours postoperatively. Such analgesic method did not affect respiratory function.
出处
《中国疼痛医学杂志》
CAS
CSCD
1997年第3期151-153,共3页
Chinese Journal of Pain Medicine
关键词
开胸术
硬膜外麻醉
镇痛
心功能
Thoracotomy
Epidural block
Analgesia
Cardiac function
