摘要
对46例65个膝关节炎(OA)采用透明质酸钠治疗,结果疼痛、晨僵、步行不适、步行距离均有明显改善。21.5%临床缓解,43.1%显效,29.2%有效,有效率达93.8%。除个别注射后关节红肿、痛外,未见其他毒副作用。注射后关节肿痛经NSAIDs治疗2天~3天缓解,且病情比注射前有所改善。透明质酸钠治疗膝OA,除缓解疼痛外,还可改善关节功能,疗效持续时间长,且无毒副作用。
The result of treatment of 46 knee osteoarthritis (OA) patients with sodium hyaluronate was that the patients' tenderness, morning stiffness and walking trouble were improved significantly. The percentages of clinical remission, obvious effect and effect were 21.5%, 43.1% and 29.2% , respectively. Redness, swelling and tenderness were observed only in a few cases and relieved following 2-3 days of NSAIDs therapy. It is concluded that hyaluronate is of therapeutic effect on knee OA, because of its tenderness relief, functional improvement, long time effect, and less side effect.