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慢性鼻及鼻窦炎鼻内镜手术疗效及黏膜上皮化分析 被引量:6

Outcome of endoscopic sinus surgery and the healing process of mucous membrane in operative cavity
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摘要 目的总结鼻内镜手术治疗慢性鼻及鼻窦炎的疗效和术腔黏膜上皮化规律,探讨影响疗效和术后黏膜上皮化的相关因素。方法对520例慢性鼻及鼻窦炎接受鼻内镜手术患者的手术疗效和术后黏膜上皮化规律进行临床分析。疗效分析应用X^2检验,黏膜上皮化时间分析用非参数秩和检验。结果治愈率74.4%,好转率21.0%,总有效率95.4%。术后平均黏膜上皮化时间为14.0周。疾病的分型分期、是否合并哮喘、变应性鼻炎和疗效与黏膜上皮化时间有相关性(P<0.05)。结论鼻内镜手术治疗慢性鼻及鼻窦炎是有效和安全的,术后黏膜上皮化时间平均需要3个月。病情重、合并哮喘或变应性鼻炎的患者疗效较差,黏膜上皮化时间长。鼻腔粘连通过定期合理的复查和处理,大多数能够得到有效的解除。 OBJECTIVE To assess the treatment outcome and healing process of the mucosa after endoscopic sinus surgery(ESS)in patients with chronic rhinosinusitis(CRS)and to research which factors could influence the clinical outcome and epithelization. METHODS Five hundred and twenty cases with chronic rhinosinusitis and nasal polyps underwent ESS from Oct.2002 to Dec.2005 were scaled with the criteria(Chinese ENT Association,1997).The clinical outcome and epithelization of mucosa after ESS were evaluated by using Chinese ENT Association criteria. RESULTS The total cure rate was 74.4%,effective rate was 95.4 %.The mean period of epithelization after operation was 14.0 weeks.There was significant difference among different types(P〈0.05).The clinical outcome and epithelization were significantly worse in patients with asthma or allergic rhinitis.The complications of ESS occurred in 73 patients(14.0 %). CONCLUSION ESS is effective in the treatment of chronic rhinosinusitis and nasal polyps.The mean term of epithelization after operation is 14.0 weeks. The outcome and epithelization process are directly related to the types of the disease.Asthma and allergic rhinitis are the factors which could influence the clinical outcome and epithelization.
出处 《中国耳鼻咽喉头颈外科》 北大核心 2008年第10期573-576,共4页 Chinese Archives of Otolaryngology-Head and Neck Surgery
关键词 鼻窦炎 内窥镜检查 上皮 治疗结果 Sinusitis Endoscopy Epithelium Treatment Outcome
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