摘要
目的分析阿立哌唑对精神分裂症患者生活质量的影响。方法采用Meta分析对5项关于阿立哌唑与其他抗精神病药物影响精神分裂症患者生活质量的文献进行再分析。结果在生理领域、心理领域、社会关系领域、环境领域五方面,阿立哌唑治疗后与治疗前组内比较效应依次为1.64、1.51、1.40、1.08、1.02,95%可信区间(CI)依次为(1.39,1.89)、(1.26,1.75)、(0.81,1.99)、(0.85,1.31)、(0.79,1.25);阿立哌唑组与对照组治疗后组间比较效应依次为1.06、0.99、1.04、0.56、0.86,95%可信区间(CI)依次为(0.83,1.29)、(0.77,1.22)、(0.45,1.64)、(0.34,0.78)、(0.28,1.44)。结论阿立哌唑改善精神分裂症患者生活质量明显,优于对照药物。
Objective To understand further the effect of aripiprazole on the quality of life in schizophrenia. Method Meta - analysis was made for 5 papers published about comparative studies of aripiprazole and other antipsychofies which affected the life quality in schizophrenia. Resullts On the aspects of physical, psychological, social relations, level of independence,environment domain, the average effects within aripiprazole group were respectively 1.64, 1.51,1.40, 1.08, 1.02,in turn,and 95% CI were（ 1.39,1.89）, （ 1.26,1.75）, （0. 81,1.99）, （0. 85,1.31 ）, （0. 79,1.25）. Average effects between aripiprazole and other antipsychoties were respectivelyl. 06,0. 99, 1.04,0. 56,0. 86, in turn, and 95% CI were （0. 83,1. 293, （0. 77,1.22）, （ 0. 45,1.64 ）, （ 0. 34,0. 78 ）, （ 0. 28,1.44 ）. Conclusion Aripiprazole can significantly improve the quality of life in schizophrenia.
出处
《四川精神卫生》
2008年第4期208-210,共3页
Sichuan Mental Health
