摘要
目的:探讨不同的随访方式对苄丙酮香豆素钠抗凝疗效的影响。方法:106例口服苄丙酮香豆素钠抗凝治疗的非瓣膜性房颤患者,随机分为专人负责的随访组和普通门诊的随访组,进行1年的治疗和观察,记录INR值和出血的发生情况。结果:与普通门诊的随访组相比,专人负责的随访组在开始治疗1个月时的达标率(92.3%)较普通门诊随访组(38.9%)明显增高,随访过程中稳定达标率(90.4%比33%)较高,发生出血和失访的情况较少,无患者自行停药,均具有显著差别。结论:专人负责的随访有利于提高苄丙酮香豆素钠的疗效。
Objective：To investigate the influence of the different style of follow-up visit to the anticoagulation effect of warfarin. Methods： 106 patients with nonvalvular atrial fibrillation who take orally warfarin for antithrombotic therapy randomized to special messenger in charge group and common clinic service group for follow-up, the value of INR, thromboembolic events and bleeding events were identified during follow-up of 1 year. Results： In the special messenger in charge group, the rate of qualification is higher after one month treatment of warfarin, and the rate kept stable during the 1-year follow-up. The incidence of bleeding events were lower, the patients lost to follow-up were less, no patient stopped medicine autonomously, The difference is significantly compared with those in the common clinical serve group. Conclusion：Special messenger in charge follow-up visit is profit to improve the effect of warfarin for antithrombolie therapy and decrease the side effect of bleeding at the same time.
出处
《中国临床医学》
北大核心
2008年第5期605-607,共3页
Chinese Journal of Clinical Medicine
关键词
非瓣膜性房颤
苄丙酮香豆素钠
抗凝治疗
Nonvalvular atrial fibrillation
Warfarin
Anticoagulative therapy
