摘要
目的分析慢性功能性便秘（chronic functional constipation，CFC）患者睡眠影响因素及肛门直肠动力学指标特征。方法67例CFC患者和同龄、同性别健康体检者（对照组）31例接受匹兹堡睡眠质量指数问卷（PSQI）评估。CFC睡眠紊乱患者和对照组同时接受抑郁自评量表（SDs）、焦虑自评量表（SAS）和肛门直肠动力学检测。结果PSQI问卷评估中，CFC组的睡眠质量、入睡时间、睡眠效率、睡眠障碍、催眠药物、日间功能障碍和PSQI总分均明显高于对照组（P〈0．05-0．01）。42例（62．7％）CFC患者存在睡眠紊乱，与对照组的一般情况和心理情绪评分比较中，前者的平均年龄、女性、平均文化程度和SAS、SDS标准分均明显高于对照组（P〈0．05）。两组的肛门直肠动力学指标比较中，睡眠紊乱CFC患者的肛门括约肌的静息压、最大缩窄压、括约肌松弛压、肛管高压区的长度检测值以及直肠感知阈值、排便阈值、疼痛闽值和引发直肠肛门抑制反射最小容积均明显高于对照组（P〈0．05～0．01）。结论CFC患者有明显的睡眠质量下降，后者与增龄、抑郁、焦虑评分、肛门外括约肌松弛不良或反常收缩以及各类肛门直肠敏感性指标增强有一定相关性。
Objective To investigate sleep behavior influencing factors and the characters of anorectal motility spectrum in patients with chronic functional eonstipation（CFC）. Methods Pittsburgh Sleep Quality Index（PSQI） was used to assess the sleep quality in 67 patients with CFC and 31 eases of the same age and sex healthy adults（control group）. The patients with CFC with sleep disorder and control group were tested by Self-Rating Anxiety Scale（SAS）, Self-Rating Depression Scale（SDS） and anorectal manometric indexes. Results The main influencing factors of PSQI scores such as sleep quality, sleep latency, sleep efficiency, sleep disturbance, use of sleep medication, daytime dysfunction were significantly different between two groups （ P 〈0.05- 0.01）. There were significant differences in age,gender,academic background,the scores of SAS and SDS between the patients with CFC with sleep disorder （42 patients,62.7 %） and control group （ P 〈 0.05）. Address resolution protocol, maximal squeeze pressure, anal canal sphincter resting pressure, anal high-pressure zone length, the sensitivity threshold, pain liminal value, defecation liminal value of anus rectum and the minimum relaxation volume of inducing anoreetal inhibitory reflex were higher in CFC group with sleep disorder than those in control group（ P 〈0.05- 0.01）. Conclusion The decrease of the somnus quality always occurs in patients with CFC, which is often complicated with aging, depression, the scores of SAS and SDS, poor relaxation or paradoxical contraction of external anal sphincter,lower sensitivity of rectum.
出处
《临床荟萃》
CAS
北大核心
2008年第22期1618-1621,共4页
Clinical Focus
关键词
便秘
睡眠障碍
因素分析
统计学
直肠
动力学
constipation
sleep disorders
factor analysis, statistical
rectum
kinetics
