摘要
目的对不同剂量瑞芬太尼在无痛人流术中麻醉效果进行系统的观察以评价其临床效果和安全性。方法需行人流术女性患者75例,随机分成瑞芬太尼1ng/ml组、瑞芬太尼2ng/ml组、瑞芬太尼3ng/ml组共三组,每组25例,观察麻醉和手术中丙泊酚用量、术后恢复时间、体动、呼吸抑制和术后腹痛情况等。结果术中瑞芬太尼1ng/ml组丙泊酚的总用量、术后恢复时间与其他两组比较,差异均有统计学意义(t分别=1.92、2.13,P均<0.05);术后呼吸抑制发生率瑞芬太尼1ng/ml组与其他两组比较,差异有统计学意义(χ2=6.24,P<0.05);三组体动发生情况及术后腹痛的发生情况相似,差异无统计学意义(P>0.05)。结论从手术安全及术后恢复的角度而言,瑞芬太尼1ng/ml作为靶控输注的效应室浓度较为合适。
Objective To investigate the efficacy and safety of painless induced abortion with use of different doses of remifentanil. Methods Seventy five patients undergoing elective abortion were divided into three groups ： remifentanil 1 ng/ml group, remifentanil 2 ng/ml group and remifentanil 3 ng/ml group. Several factors including the dose of propofol, recovery time after anesthesia, body movement, respiration weakness and post-operation bellyache ete were observed. Results The total doses of propofol during anesthesia and recovery time after anesthesia in the remifentanil 1 ng/ml group were different from that in the other two groups （t=1.92, 2.13, P〈0.05）. The rate of respiration weakness in the remifentanil 1 ng/ml group was different from that in the other two groups （χ^2=6.31 ,P〈 0.05）. The body movement and post-operation bellyache were similar in the three groups without statistic significance. Conclusion Considering about safety and postoperative recovery, target-controlled infusion of lng/ml remifentanil used in painless induced abortion had some advantages.
出处
《全科医学临床与教育》
2008年第5期375-377,共3页
Clinical Education of General Practice
关键词
瑞芬太尼
无痛人流
剂量
remifentanil
painless induced abortion
dose
