摘要
目的了解不动杆菌检出的临床分布及耐药性变化。方法分析中山大学附属第一医院2005～2007年从住院病人分离出的不动杆菌的药物敏感试验结果及其分布情况。菌株用VITEK-2全自动细菌鉴定仪鉴定,药敏试验用VITEK-2配套的GNS药敏卡测定。结果3年间共分离不动杆菌446株,其中以鲍曼氏不动杆菌为主,分离出395株,占不动杆菌总数的88.6%,其次为鲁氏不动杆菌29株(6.5%)。感染部位以呼吸道为主(75.8%),其次为血液感染(4.3%)。不动杆菌对头孢哌酮/舒巴坦、亚胺培南、美罗培南耐药率低,均<20%。对大部分抗生素的耐药性有逐年增加的趋势。结论头孢哌酮/舒巴坦、亚胺培南、美罗培南对不动杆菌保持良好的抗菌活性,应注意合理使用抗生素,减少耐药菌株的产生。
Objective. To investigate the distribution and drug resistance ofAcinetobacter spp. in our hospital. Methods The drug resistacne of ofAcinetobacter spp . isolated from 1 st January 2005 to31 st December 2007 in our hospital was monitored. Results There 446 strains of Acinetobacter spp. were isolated including 395 strains of Acinetobacter baumannii （88.6%） , 29 strains ofAcinetobacter lwoffii （6.5%）. There 75.8% Aeinetobacter spp were isolated from respiratory samples, 4.3% from blood samples . The resistance rates of Aeinetobacter spp to eefoperazone/sulbaetam, imipenem, meropenem were all less than 20%. Conclusion Acinetobacter spp show low resistance to cefoperazone/sulbactam, imipenem, meropenem. But rational use of antibiotics is necessary for delay the development of drug reissitance.
出处
《中国热带医学》
CAS
2008年第11期2029-2030,共2页
China Tropical Medicine
关键词
不动杆菌
感染
耐药
Acinetobacter
Infection
Drug resistance
