期刊文献+

124例肺血栓栓塞症的临床分析

Clinical analysis of 124 pulmonary thromboembolism
原文传递
导出
摘要 目的对本院1998~2006年189例肺血栓栓塞症(pulmonary thromboembolism,PTE)患者中资料完整的124例进行临床回顾性分析。方法诊断标准符合中华医学会呼吸病学会制定的诊断标准,对所有124例PTE患者的病史、临床表现、心电图、X线胸片、血气、下肢深静脉超声、彩色多普勒心脏超声、螺旋CT肺血管造影(CTPA)、肺通气/灌注扫描(V/Q显像)等临床资料进行分析。结果PTEDVT年发病数逐年增加。大面积PTE 83例(66.9%),次大面积PTE 20例(16.1%),非大面积PTE 21例(16.9%)。DVT70例,术后40例.长期卧床65例,恶性肿瘤6例,结缔组织病3例,睡眠呼吸暂停低通气综合症1例。所有患者均有不同程度的呼吸困难,心悸90例。胸痛30例,咯血19例,咳嗽40例,晕厥16例,突然心跳、呼吸停止机械通气5例。呼吸频率〉20次/min 86例,心率〉100次/min 112例,发绀65例,肺部闻及干湿哕音22例。PaO2〈60mm Hg 72例。PaCO2〈35mm Hg 92例,PaCO2〉35mm Hg 32例;心电图窦速112例。SⅠQⅢTⅢ型改变者25例,CRBBB型改变26例,非特异性S-T改变舵例,窦性心动过缓5例;胸部X线检查有阴影者20例,行CTPA检查105例,V/Q显像18例,肺动脉造影1例;心脏超声显示右心室扩张合并肺动脉高压共91例,20例仅有肺动脉高压,无右心室扩大,8例心脏超声完全正常。首诊24h内确诊72例,其余52例确诊时间为2~60d,误诊率为30%(37例),其中误诊为冠心病、急性左心衰、肺炎者最多。溶栓抗凝治疗83例,单纯抗凝治疗41例,死亡8例(6.5%)。结论PTE的发病呈逐年增高的趋势;特别要注意恶化肿瘤和结缔组织病是重要的易感因素;PTE最常见的症状是呼吸困难。因此,提高临床医生的诊断意识,以减少漏诊和误诊。 Objective To retrospectively analyse the clinical characteristics of 124 pulmonary thromboembolism(PTE) patients adimitted in the hospital from 1998 to 2006. Methods A total of 178 PTE patients were diagnosed in the hospital, of which 124 cases had complete medical documents. All the cases met the criteria set by the respiratory division of Chinese Medical Society. The clinical characteristics,results of auxiliary examinations such as ECG,chest x ray,blood gas analysis, ultrasound of lower limb deep veins, echocardiograph,CTPA and V/Q scan were recorded and analysed. Results PTE patients increased year by year. Massive, suhmassive and non-massive area cases were 83 ( 66.9 %), 20 ( 16.1 %), 21 ( 16.9% ). Among the patients, the main risk factors were DVT ( 70 cases), surgery ( 40 cases), immobility( 65 cases), tumor ( 6 cases), connective tissue disease ( 3 cases), OSAS ( 1 case). The main symptoms were dyspnea ( 100% ), palpitation(90 cases), chest pain(30 cases), haemoptysis (19 cases), cough(40 cases), syncope( 16 cases), cardiac respiratory arrest(5 cases) by turns. The main findings of physical examinations were rapid breath rate( 〉 20 times/min) (86 cases), rapid heart beating( 〉 100 beats/min) ( 112 cases), cyanosis( 65 cases), dry and wet rales(22 cases). The main meaningful findings of lab tests were: PaO2 〈 60 mm Hg( 72 cases), PaCO2〈35 mm Hg(92 cases),PaCO2〉35 mm Hg(32 cases);ECG:sinus tachycardia:112 cases,SⅠ QⅢ TⅢ (25 cases),CRBBB 26 cases, non-specific S-T changes 42 cases, sinus bradycardia(% 60 beats/rain) 5 cases chest x-ray:Wedge shape(20 cases),positive result of CTPA(105 cases), high probobility of V/Q scan (18 cases); echocardiograph: right ventricular dilatation, pulmonary hypertension 91 cases, 20 cases, only 8 patients had a normal echocardiograph examination. Only 72 patients got confirmed diagnosis in the first 24 hours of admission,other 52
出处 《国际呼吸杂志》 2008年第20期1231-1233,共3页 International Journal of Respiration
关键词 肺血栓栓塞症 误诊 预防 Pulmonary thromboembolism Misdiagnosis Prevention
  • 相关文献

参考文献4

二级参考文献10

  • 1De Gregorio MA,Gimeno MJ,Mainar A,et al.Mechanical and enzymatic thrombolysis for massive pulmonary embolism.J Vasc Interv Radiol,2002,13:163-169. 被引量:1
  • 2Stein PD,Afzal A,Henry JW,et al.Fever in acute pulmonary embolism.Chest,2000,117:39-42. 被引量:1
  • 3Miniati M,Prediletto R,Formichi B,et al.Accuracy of clinical assessment in the diagnosis of pulmonary embolism Am J Respir Crit Care Med,1999,159:864-871. 被引量:1
  • 4Aburahma AF,Saiedy S.Deep vein thrombosis as a probable cause of fever of unknown origin.W V Med J,1997,93:368-370. 被引量:1
  • 5Stallman JS,Aisen PS,Aisen ML.Pulmonary embolism presenting as fever in spinal cord injury patients:report of two cases and review of the literature.J Am Paraplegia Soc,1993,16:157-159. 被引量:1
  • 6武燕兵,王辰..临床表现..王辰,著..肺栓塞..北京:人民卫生出版社,,2003..141-151.. 被引量:2
  • 7Calvo-Romero JM,Perez-Miranda M,Bureo-Dacal P.Syncope in acute pulmonary embolism.Eur J Emerg Med,2004,11:208-209. 被引量:1
  • 8肺血栓栓塞症的诊断与治疗指南(草案)[J].中华结核和呼吸杂志,2001,24(5):259-264. 被引量:1838
  • 9高金明,李梦涛,田新平,蔡柏蔷,李龙芸.原发性抗磷脂综合征合并肺血栓栓塞症四例[J].中华内科杂志,2002,41(2):130-131. 被引量:3
  • 10伍燕兵,杨媛华,王辰.肺血栓栓塞症的临床表现[J].中华医学杂志,2003,83(3):260-261. 被引量:28

共引文献1980

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部