摘要
近距离放疗是鼻咽癌治疗的主要手段之一。其计算机仿真可帮助医生制定详细的放疗方案,对鼻咽癌精确放疗具有显著意义。一个完整的鼻咽癌近距离放疗仿真的方案被提出。首先,对CT图像进行分割,重建三维组织模型。然后,设计了基于Ta-chih Lee细化算法的鼻咽腔放疗源虚拟输送路径。最后,对125I柱状放射源放射剂量分布进行了蒙特卡罗仿真。初步实现了鼻咽癌近距离放疗的计算机仿真。
Brachytherapy is one of the major means of nasopharyngeal carcinoma treatments. Computer simulation of the process is of great value to radiotherapy planning. A complete solution for computer simulation of nasopharyngeal carcinoma brachytherapy was proposed. Firstly,the CT images of the nasopharyngeal tissues were segmented and the 3D models of nasopharyngeal tissues were reconstructed. Then the 3D delivery path of radioactive source based on Ta-chih Lee’s thinning algorithm was designed. Finally,the simulation of cylindrical 125I dose distribution was realized by Monte Carlo method. A primary computer simulation of nasopharyngeal carcinoma Brachytherapy was realized.
出处
《系统仿真学报》
EI
CAS
CSCD
北大核心
2008年第20期5543-5547,共5页
Journal of System Simulation
基金
国家自然科学基金项目(60601025)
福建省科技重点项目(2005Y0018)
关键词
鼻咽癌近距离放疗
放射源
剂量分布
放疗路径提取
蒙特卡罗仿真
nasopharyngeal carcinoma brachytherapy, radioactive source, dose distribution, path planning, Monte-Carlo simulation
