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葡萄糖酸锌治疗小儿轮状病毒腹泻332例疗效观察 被引量:16

Clinical observation of therapeutic effect of zinc gluconate on infantile rotavirus diarrhea
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摘要 目的观察葡萄糖酸锌治疗小儿轮状病毒腹泻的有效性及安全性。方法332例小儿轮状病毒腹泻被随机分为两组,治疗组在常规治疗基础上加用葡萄糖酸锌治疗;对照组常规治疗。结果治疗组总有效率为92.07%,对照组总有效率为74.41%,两组差异有统计学意义(P<0.01)。在止泻时间和总疗程方面治疗组短于对照组,两组差异有统计学意义(P<0.01)。末见不良反应。结论葡萄糖酸锌治疗小儿轮状病毒腹泻临床疗效确切,无明显不良反应,方法简便,价廉易得,易于接受,适于推广。 Objective To observe the efficacy and safety of of zinc gluconate treating infantile rotavirus diarrhea. Methods Three hundred and thirty two children patients with rotavirus diarrhea were randomly divided into treatment group (on basis of conventional therapy,zinc gluconate was given) and control group (receiving conventional therapy). Results The total effective rate in treatment group was significantly higher than that of control group (92.07% vs 74.41%,P〈0.01). Compared with those of control group, the time of checking diarrhea and treatment course were markedly shorter in treatment group (P〈0. 01). No adverse reaction occurred in treatment group. Conclusion Zinc gluconate therapy is effective,safe, convenient,economic,and acceptable in treatment of infantile rotavirus diarrhea,worthy of spreading.
作者 杨英 梅其霞
出处 《重庆医学》 CAS CSCD 2008年第21期2442-2442,2445,共2页 Chongqing medicine
关键词 小儿轮状病毒腹泻 葡萄糖酸锌 有效性及安全性 infantile rotavirus diarrhea zinc gluconate efficacy and safety
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