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沐舒坦防治早产儿呼吸窘迫综合征的疗效观察 被引量:1

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摘要 目的探讨沐舒坦防治早产儿呼吸窘迫综合征(RDS)的疗效。方法以沐舒坦治疗组为观察组,以单纯综合治疗组为对照组。观察组在综合治疗基础上于生后4h内给以沐舒坦每次7.5mg/kg,每6h1次,疗程3~5d。观察2组早产儿RDS的发病率、临床表现、X线表现、机械通气开始时间、机械通气时间、下机后氧疗时间及死亡率情况。结果2组早产儿RDS的发病率、临床表现、X线表现差异无统计学意义;观察组机械通气开始时间(7.9±0.91)h,对照组(8.2±0.98)h,2组相比差异无统计学意义(P>0.05);观察组机械通气时间(70.5±4.78)h,对照组(83.14±8.31)h,2组相比差异无统计学意义(P>0.05);2组下机后氧疗时间,观察组(18.32±0.64)h,对照组(26.37±0.39)h,差异有统计学意义(P<0.01);2组死亡率相比差异无统计学意义(P>0.05)。结论早产儿生后早期应用沐舒坦,能够促进肺表面活性物质生成和分泌,有利于促进肺发育成熟,促进早产儿RDS临床过程的改善,有利于疾病的恢复。
作者 金扬 罗瑶佳
出处 《中国医学文摘(儿科学)》 2008年第5期368-369,共2页
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