摘要
目的:检测新疆医科大学第一附属医院臂踝脉搏波传导速度(baPWV);评价PWV的临床应用价值。方法:(1)收集受试患者的病史、生化检查和临床用药情况资料;(2)测定新疆医科大学一附院1500例30岁以上住院患者测定baPWV,根据结果分为两组:(1)baPWV<1400cm/s组(n=395);(2)baPWV≥1400cm/s组(n=1105)。通过多因素logistic回归分析baPWV的相关因素。结果:baPWV≥1400cm/s组平均年龄明显高于baPWV<1400cm/s组,身高明显低于baPWV<1400cm/s组。baPWV≥1400cm/s组更多伴有糖尿病、冠心病、脑卒中、高血压(P<0.05)。单因素分析提示总胆固醇、低密度脂蛋白胆固醇、空腹血糖、收缩压、舒张压、脉压与baPWV正相关,吸烟史与baPWV负相关;多因素logistic回归分析显示年龄、脉压增大、高血压是baPWV增快的危险因素。结论:年龄、脉压和身高是baPWV的主要影响因素;baPWV与全身性动脉粥样硬化具有相关性,应成为临床的常规检查。
Objective：To detect brachial-ankle pulse wave velocity（baPWV）of in patients in ourhospital and to evaluate value of clinical application of baPWV.Methods：（1）A total of 1 500 patients（age more than 30）were recruited.The medical history,symptoms,exam of biochemistry and clinical medication of each subject were confirmed by the consulting doctors.（2）Noninvasive brachial-ankle pulse wave velocity measurement baPWV was measured using a volume-plethymographic apparatus.Based on baPWV index,we divided the patients for two sets：① baPWV〈1 400 cm/s（n=395）and ② baPWV≥1 400 cm/s（n=1 105）.Then the correlation factor of baPWV analyed by mono factor and multiple factor logistic regression analysis.Results：① Mean age in baPWV≥1 400cm/s group was older than baPWV〈1 400 cm/s group.But lower than baPWV〈1 400 cm/s group in patients＇s stature.And baPWV≥1 400 cm/s group had comodalities,such as diabetes,coronary artery disease（CHD）,stroke and hypertension（HBP）（P〈0.05）;② Analysed by monofactor analysis：The total cholesterol（TC）,low density lipoprotein cholesterol（C-LDL）,blood-fasting sugar（BFS）,systolic blood pressure（SBP）,diastolic blood pressure（DBP）and pulse pressure（PP）have direct correlation with baPWV.And history of smoking has negative correlation with baPWV.③Analysed by multiple factor logistic regression analysis：to show the age,PP increasing,HBP were risk factor of baPWV increasing.Conclusion：The age,PP and stature are main influential factor of baPWV;There are dependablity between baPWV and artherosclerosis.baPWV should be a general clinical routine examination.
出处
《新疆医科大学学报》
CAS
2008年第9期1159-1161,共3页
Journal of Xinjiang Medical University
基金
新疆自治区重点学科内科学一期建设经费(2005-区教委-01)
