摘要
目的分析急性脑卒中中合并多器官功能障碍综合征（MODS）患者的发生率、病死率及相关危险因素。方法回顾性分析1240例急性脑卒中中合并MODS128例患者的临床资料。结果本组MODS发生率为10．3％，死亡72例，病死率为56．3％。单因素结果分析显示病死率随着受累器官数目的增加而增加，死亡组与存活组比较，年龄、体温、血糖、肌酐均较高，神经功能缺损较重；经Logistic回归分析，既往健康状况、衰竭器官的数目、神经功能缺损的分值为主要死亡因素，病变部位靠近中线及基底动脉系统者MODS的发生率高。结论MODS多发生在急性脑卒中后2周内，提示MODS的防治除控制原发病外，还应对易受累脏器采取积极治疗措施，并强调全身综合治疗的重要性。
Objective To investigate the incidence, case fatality and risk factors of acute stroke complicated by multiple organ dysfunction syndrome （MODS）. Methods A retrospective study was conducted in 1 240 patients with acute stroke among whom 128 patients also developed MODS. Results The incidence of MODS in these patients was 10.3% with case fatality of 56. 3%. The increased number of organ involved resulted in higher case fatality. Compared with the survival group, the death group had a higher level on age, temperature, blood glucose and creatinine and it was more serious on neurologic impariment. Through Logistic regression analysis,we found the chief factors of death were the health status in the post,the numbers of faliure organ and the degree of neurologic impairment. When the diseased region was adjacent to median line or basal artery system,there was a higher incidence rate Of MODS. Conclusion MODS usually occurs in two weeks after the onset of acute stroke. Prevention of MODS involves rigorous treatment of the compromised organs and comprehensive systemic therapy in addition to the management of the primary diseases.
出处
《中国实用医刊》
2008年第20期16-17,共2页
Chinese Journal of Practical Medicine
