摘要
对毛细管筛分电泳在ＤＮＡ片段多态性分析中的应用作了较为详细的论述，还对ＤＮＡ片段多态性研究的意义和作用进行了讨论。
A review is given here to describe the principle and methods of gene polymorphism analysis by capillary electrophoresis (CE). DNA length polymorphism and sequence polymorphism are very important phenomena in gene molecular biology. Some practical works of gene length polymorphism analysis and sequence polymorphism analysis are listed. SSCP and HPA methods detecting gene point mutations are demonstrated. Applications of gene polymorphism analysis by CE in clinical forensic and biological research are also discussed in this paper.
出处
《色谱》
CAS
CSCD
北大核心
1997年第4期301-304,共4页
Chinese Journal of Chromatography
基金
国家自然科学基金
关键词
毛细管电泳
DNA片段
多态性
capillary electrophoresis, DNA fragments, polymorphism
