摘要
目的探讨脑血管病(CVD)与睡眠呼吸障碍(SDB)的相关性。方法利用多导睡眠图(PSG)对40例急性脑血管病患者进行睡眠全程监测,并选择年龄、性别和体重指数(BMI)相当的健康体检者32例作为正常对照组。结果研究组睡眠结构紊乱,表现为睡眠效率降低、深睡期和快速眼动(REM)睡眠时间减少、浅睡时间延长,与正常对照组比较,差异均有统计学意义(P<0.01);同时与正常对照组比较,研究组呼吸暂停时间和睡眠呼吸暂停/低通气指数(AHI)明显增高(P<0.01),动脉氧饱和度(SaO2)明显降低(P<0.01),34例(85%)诊断为睡眠呼吸暂停综合征。其中阻塞型睡眠障碍20例(58.8%)(OSA)。结论睡眠呼吸障碍,尤其是OSA与脑血管病的关系密切,既是其发病的独立危险因素,又受其影响加重。
Objective To investigate the relationship between cerebrovascular disease （CVD） and sleep - disordered breathing （SDB）. Methods Polysomnography（PSG）in 40 patients with CVD and 32 cases who in age,sex and body mass index（BMI） matched healthy control subjects was monitored. Results In the study group, the patients presented the disturbance of sleep structure, with the mean percentage of sleep efficiency, both deep sleep stage （3 and 4 ）and rapid eye movement（ REM ）sleep were significantly lower in the patients than in healthy control subjects （ P 〈 0.01 ） ; the mean sleep stage （ 1 and 2 ） was significantly higher in the study group than in healthy control group（ P 〈 0.01 ）. Sleep apnea syndrome was found in 34 of 40 patients（85% ） with CVD, meanwhile obstructive sleep apnea syndrome （OSAS）was found in 20 of 34 patients （58.8%）with the former, apnea time and apnea/hypopnea index（ AHI）were significantly higher in the study group than in healthy control group（ P 〈 0.01 ） ; SaO2 were significantly lower in the patients than in healthy control group（ P 〈 0.01 ）. Conclusion There was a close relationship between SDB, especially OSAS and CVD. SDB was not only the risk of CVD, but also was deteriorated by it.
出处
《临床医学》
CAS
2008年第9期3-5,共3页
Clinical Medicine
关键词
脑血管病
睡眠呼吸障碍
多导睡眠图
Cerebrovascular disease
Sleep - disordered breathing
Polysomnography
