摘要
目的了解2142例男性可疑非淋球菌性尿道炎（NGU）患者泌尿生殖道衣原体、支原体感染及药敏状况。方法应用衣原体试剂盒（胶体金法）定性检测衣原体。支原体培养及药敏选用支原体药敏试剂盒，并用10种抗生素对支原体的敏感性进行分析。结果2142例可疑NGU患者中，衣原体阳性241（11．25％）例，支原体阳性者566（26．42％）例，在支原体阳性者中解脲脲原体512例（90．5％），人型支原体12例（2．1％），解脲脲原体合并人型支原体感染42例（7．4％）。支原体敏感药物多是多西环素、交沙霉素、米诺环素，耐药多是环丙沙星、氧氟沙星、克林霉素。结论NGU患者的病原体仍然是衣原体、支原体。治疗支原体感染的首选药为多西环素、交沙霉素、米诺环素。进行支原体培养鉴定和药敏试验，可以根据药敏结果指导临床合理使用抗生素。
Objective To investigate the status of pathogens and antimicrobial susceptibility in 2142 male patients with nongonococcal urethritis（NGU）. Methods Urethral specimens from 2142 cases of male patients with NGU were collected and detected for C. trachomatis（CT） by a CT kit and U. urealyticum（UU） by culture. Antimicrobial susceptibility testing to 10 commonly used antibiotics was carried out at the same time. Results Positive CT were found in 241patients（ 11.25% ）. Positive Mycoplasma in 566 pantients（26.42% ） ,512（90.5% ） of which were Ureaplasma Urealyticm（UU） ,12（2. 1% ）were Mycoplsma homints（Mh）. Both UU and Mh were identified in 42（7.4% ） specimens. Most strains of UU and MH were susceptible to Monodoxin, Clindamycin. Conclusions The main pathogens for NGU are UU and CT. The best choice to treat Mycoplasma may have variable susceptibility to the same kind of antibiotic. Active culture, indentification, and susceptibility testing of mycoplsme can provide useful information for rational use of antibiotics.
关键词
衣原体
支原体
感染调查
药敏试验
Mycoplasma Chlamydia Survey of infection Drug sensitive test
