摘要
目的对国产与进口阿德福韦酯治疗慢性乙型肝炎进行成本-效果分析。方法选择门诊慢性乙型肝炎患者98例,随机分为A、B两组。A组47例,给予进口阿德福韦片10mg/d;B组51例,给予国产阿德福韦胶囊10mg/d,两组均添加胸腺肽肠溶片15mg/d,疗程104周。定期检测两组的ALT复常率、HBV-DNA阴转率、HBeAg抗HBe血清转换率。结果A组的总成本为15 913.5元,B组的总成本为10 251.5元,104周治疗结束后,两组的有效率比较无显著性差异。结论国产阿德福韦酯的成本-效果比优于进品阿德福韦酯,为较优的治疗方案。
Objective To study the cost-effectiveness analysis on the patients with chronic hepatitis 13 treated with domestic or imported adefovir dipivoxil. Methods 98 patients With chronic hepatitis were divided into A group and B groups. A group of 40 patients and B group of 58 patients were treated with imported and domestic adefovir dipivoxil, respectively. The rate of ALT normalization, HBV-DNA conversed, anti-HBe HBeAg conversed were observed. Results After 104 weeks treatment, the total costs of A group and B group were 15913, 5 yuan and 10251.5 yuan, respectively. The curative effect of two groups was not obviously different. Conclusion The cost effectiveness of domestic adefovir dipivoxil is superior to that of imported one for chronic hepatitis B patients.
出处
《西部医学》
2008年第6期1276-1278,共3页
Medical Journal of West China
关键词
慢性乙型肝炎
阿德福韦酯
成本
效果
Chronic hepatitis B
Adefovir dipivoxil
Cost
Effectiveness
