摘要
为探讨恶性血液病侵犯中枢神经系统的发病情况及治疗监护，用玻片离心沉淀法脑脊液细胞学检查对１３６例小儿恶性血液病６１２份标本进行研究，病例的肿瘤细胞阳性率ＡＬＬ为５３．５％，ＡＮＬＬ为３８．１％，ＬＳＬ为４５．５％，ＮＨＬ为２７．８％，ＮＢ为１１．１％。与常规三项检查比较，脑脊液细胞数≥１０×１０６／Ｌ和＜１０×１０６／Ｌ，标本间阳性率有明显差异（Ｐ＜０．０１）。有中枢神经系统临床症状、体征的２０例，肿瘤细胞阳性率为９５．０％。该方法简单、快速、敏感，对恶性血液病浸润神经系统的诊断、治疗监护有意义。
Cerebrospinal fluid (CSF) cytology of 612 specimens obtained from 136 cases of childhood malignant hematonosis were examined by slide centrifugated sedimentation (SCS) The result showed that the positive rate of tumor cells was 53 5% in acute lymphocytic leukemia,38 1% in acute non lymphocytic leukemia,45 5% in lymphosarcoleukemia,27 8% in non hodgkins lymphoma,and 11 1% in neuroblastoma respectively Comparing SCS with the routine 3 items examination,the positive rates of tumor cells between ≥10×10 6/L and <10×10 6/L cell count in CSF speciems were significantly different (P<0 01).The positive rate of tumor cells was 95 0% in 20 patients with symptoms and signs of the central nervous system Hence,SCS is a simple,quick and sensitive method,which can be used in the diagnosis and evaluation of the treatment of malignant hematonosis with CNS infiltration
出处
《广西医科大学学报》
CAS
1997年第2期49-52,共4页
Journal of Guangxi Medical University
关键词
脑脊液
细胞学
恶性血液病
儿童
cytology
cerebrospinal fluid
malignant hematonosis
