摘要
炎症性肠病(inflammatory bowel disease,IBD)的患病率正不断上升,但其确切的病因和发病机制仍不清楚.对肠道抗原与IBD之间关系的研究为其发病机制的认识提供了新方向.本文详述了肠道抗原识别与IBD在临床表型、预后及家族遗传间的关系,为其进一步治疗IBD提供指导.
The incidence of inflammatory bowel disease （IBD） is increasing all over the world. However, it is rather difficult to treat IBD because its etiological factors and pathogenesis are still not clear. In recent years, the researches about the relationship between luminal bacterial antigens and IBD have provided new advances for its etiology and pathogenesis. We, in this paper, describe the present status in the recognition of luminal bacterial antigens in IBD patients which is correlated to the clinical phenotypes, prognosis and familial genetics of this disease, thus contributing to the treatment for IBD.
出处
《世界华人消化杂志》
CAS
北大核心
2008年第28期3192-3196,共5页
World Chinese Journal of Digestology
关键词
肠道细菌
抗原识别
炎症性肠病
Luminal bacteria
Antigen recognition
Inflammatory bowel disease
