体细胞克隆的小鼠胚胎在附植前后发育的研究
摘要
采用成年小鼠的卵丘细胞核、胎儿成纤维细胞作核供体细胞来进行核移植,研究小鼠卵母细胞的去核程序和影响重构胚附植前发育的激活条件;随后将重构胚与供体细胞系共培养后获得囊胚阶段的小鼠重构胚,并将其移植到受体鼠体内后获得了24%克隆胚胎。结果表明,小鼠卵母细胞质能够进行重编程来支持早期的胚胎发育。
出处
《广东畜牧兽医科技》
2008年第5期32-36,共5页
Guangdong Journal of Animal and Veterinary Science
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