摘要
Many primary,secondary,tertiary alcohols,and phenolic hydroxyl groups were effectively converted to their corresponding trimethylsilyl ethers using hexamethyldisilazane in the presence of catalytic amounts of tribromoisocyanuric acid and DABCO-bromine under mild conditions at room temperature with short reaction times in good to excellent yields.Excellent chemoselective silylation of hydroxyl groups in the presence of other functional groups were also observed.
Many primary, secondary, tertiary alcohols, and phenolic hydroxyl groups were effectively converted to their corresponding trimethylsilyl ethers using hexamethyldisilazane in the presence of catalytic amounts of tribromoisocyanuric acid and DABCO-bromine under mild conditions at room temperature with short reaction times in good to excellent yields. Excellent chemoselective silylation of hydroxyl groups in the presence of other functional groups were also observed.
出处
《催化学报》
SCIE
EI
CAS
CSCD
北大核心
2008年第9期901-906,共6页
基金
Supported by Bu-Ali Sina University Research Council.
关键词
DABCO-溴
催化剂
催化作用
化学分析
tribromoisocyanuric acid
DABCO-bromine
hexamethyldisilazane
silylation
hydroxyl group
