摘要
目的:研究急性中毒患者血清肿瘤坏死因数-α(TNF-α)、白细胞介素-6(IL-6)的水平与APACHEⅡ评分的相关性,并探讨其临床意义。方法:采用ELISA法检测38例急性中毒患者血清TNF-α、IL-6水平,并进行APACHEⅡ评分。结果:38例急性中毒患者血清TNF-α、IL-6水平均高于正常对照组(P<0.01),与APACHEⅡ评分呈正相关(P<0.01)。结论:同步检测细胞因子活性及进行APACHEⅡ评分,有助于急性中毒患者病情评估及预后判断。
Objective： To investigate the correlation between the levels of plasma tumor necrosis factor-α（TNF- α） ,interleukin-6 （IL-6）and APACHE Ⅱ in acute poisoning. Methods： ELISA methods were used to determine the TNF-α,IL-6 levels in acute poisoning, and APACHE Ⅱ evaluated. Results： Levels of TNF-α,IL-6 in acute poisoning were significantly higher than normal controls （P 〈0.01）. There were significant positive correlation between inflammatory cytokines and APACHE Ⅱ （P〈0.01）. Conclusion： The assay of in inflammatory eytokines and APACHE Ⅱ may be helpful for evaluation of acute poisoning and prognosis.
出处
《岭南急诊医学杂志》
2008年第3期209-210,共2页
Lingnan Journal of Emergency Medicine
