摘要
造血干细胞移植(hemopoietic stem cell transplantation,HSCT)是通过异体或自体的造血干细胞(HSC)植入受者体内,而使受者获得造血和免疫功能重建的方法。随着实验血液学、临床血液学和移植免疫学的不断发展,特别是人类白细胞抗原(HLA)配型技术的发展,使HSCT技术逐渐成熟并广泛应用,成为治愈某些恶性血液病的重要方法。脐带血作为HSC的来源之一,已成功应用于临床,并有望在今后的生物学治疗和基因治疗中发挥重要的作用。本文就近年来有关脐带血HSCT移植的研究进展作一综述。
Hemopoietic stem cell transplantation is a technology that recipient will gain hematopoiesis and immune function reconstruction through variant or autogeneic hemopoietic stem cell transplant into the body. Following the development of experiment hematology, clinical hematology and transplantation immunology, especially human leucocyte antigen zygosity technology, hemopoietic stem cell transplantation technique is gradually becoming maturity and widespread used, and becoming very important in cure of malignant hematologic disease. The umbilical cord blood has been used in clinic treatment asone resource of hematopoietic stem cell and will play an important role in biotherapy and gene therapy in future. This paper reviews the research progress of the umbilical cord hemopeietic stem cell transplantation for the past few years.
出处
《内蒙古医学院学报》
2008年第4期292-296,共5页
Acta Academiae Medicinae Neimongol
基金
内蒙古财政厅基金资助项目(内财教[2005]1162号)
内蒙古自治区人才基金(2005)
关键词
脐带血
造血干细胞
移植
umbilical cord blood
hemopoietic stem cell
transplantation
