摘要
目的探讨孕妇孕期增重及各孕期体重增加速度与分娩巨大儿的相关性，减少巨大儿的发生率。方法采用病例对照研究方法，将106例巨大儿和109例正常体重出生儿（对照组）母亲的孕前体重及孕期体重变化等资料作一回顾性分析。结果经过单因素和多因素非条件logistic回归分析表明，孕前体重（OR=2．204，95％CI：1．377～3．529）、孕12～20周体重增加速度（kg／周，OR=1．961，95％CI：1．204～3．194）、孕20～30周体重增加速度（kg／周，OR=1．811，95％CI：1．078～3．041）、孕30周至产前体重增加速度（kg／周，OR=1．858，95％CI：1．095～3．153）、男性婴儿（OR=2．630，95％CI：1．420～4．850），是发生巨大儿的危险因素。值得注意的是孕30周后每周体重增加在0．5～1．0kg的孕妇比每周体重增加在0．5kg以下的孕妇发生巨大儿的风险增加1．13倍（OR=2．13，95％CI：1．07～4．22）。结论巨大儿的发生与孕妇孕前体重、孕期增重、胎儿性别等因素相关。
Objective To investigate the relationship between maternal weight gain and the increasing speed of weight in different pregnant terms and macrosomia. In order to reasonably manage pregnancy and decrease the morbidity of macrosomia. Methods 106 newborns whose birth weights were equal to or greater than 4000 g were specified as macrosomia, while 106 newborn with birth weights lying in 2500-3999 g were under the control group. A case-control study was conducted to compare the corresponding factors such as maternal BMI, weight before pregnancy and the change of weight during pregnancy respectively. Results Indicated by both simple and multiple unconditional logistic regression analysis, the cause of fetal maerosomia was mainly associated with the factors including the maternal weight before pregnancy （ OR = 2. 204,95 % CI ： 1. 377-3. 529）, maternal weight gain in 12- pregnant weeks （ kg per week） （OR = 1.961,95% CI： 1.204-3. 194）, maternal weight gain in 20- gestation weeks （kg per week） （ OR = 1. 811,95 % CI ： 1. 078-3. 041 ）, maternal weight gain in 30- pregnant weeks （kg per week） （ OR = 1. 858,95 % CI ： 1. 095-3.153） and virile newborn （ OR = 2. 630,95 % （21 ： 1. 420-4. 850. When in 30-pregnant weeks, the pregnant women with 0.5-1,0 kg weight gain per week had 1.13 fold risks comparing to those whose weight gains were less than 0.5 kg per week. Conclusion Maternal weight before pregnancy, weight gain during pregnancy and fetal sex appeared a closer relation to macrosomia. It is necessary to monitor the change of maternal weight during different pregnancy periods, especially for the 30th- pregnant weeks.
出处
《中华流行病学杂志》
CAS
CSCD
北大核心
2008年第10期982-984,共3页
Chinese Journal of Epidemiology
