摘要
目的:研究血小板活化因子乙酰水解酶基因突变(Ala379Val)与银屑病的关系。方法:对60例银屑病患者及60例健康对照者,分别用聚合酶链反应技术(PCR)及测序分析基因组DNA的突变等位基因。结果:银屑病组血小板活化因子乙酰水解酶基因突变率(Ala379Val)与健康人群无显著差异(P>0.05)。结论:血小板活化因子乙酰水解酶基因突变可能与银屑病的发病无关。
Objective： To investigate the correlation between the gene mutation of platelet - activating factor acetylhydrolase and psoriasis. Methods： Genomic DNA was analyzed for the mutation allele in 60 patients with psoriasis and 60 healthy controls by polymerase chain reaction. Results： There was no significant difference in the gene mutation rate between the patients and controls （ P 〉 0.05）. Conclusion： The mutation rate of platelet - activating factor acetylhydrolase is not related with psoriasis.
出处
《中国麻风皮肤病杂志》
2008年第9期686-688,共3页
China Journal of Leprosy and Skin Diseases
