摘要
目的了解血液病住院发生医院内感染患者中分离细菌的分布及其耐药情况。方法收集住院患者临床分离菌株，用最小抑菌浓度（MIC）法进行药敏试验。结果各种标本中分离出细菌56株，主要分布于血液、痰液、尿液等，革兰阳性细菌占14．3％，革兰阴性细菌占85．7％。革兰阴性细菌中以大肠埃希菌和铜绿假单胞菌最多，各有12株，分别占革兰阴性细菌的21．4％。大肠埃希菌和肺炎克雷伯菌产ESBLs菌株的检出率分别为75．0％（8／12）和33．3％（2／6）。结论上述结果对血液系统疾病合并感染患者的经验性用药有重要的参考价值。
Objective To survey the distribution and antibiotic resistance of bacterium isolated from hospitalized patients with hematological diseases. Methods Bacterial strains were isolated from patients with hematological disease. Antimicrobial susceptibility testing was done by the method of minimum inhibitory concentration. Results A total of 56 bacterial strains were isolated from all kinds of specimens, including blood,phlegm and urine. 14.3 % were gram-positive and 85.7 % were gram-negative bacterium. Escherichia coli and pseudomonas aeruginosa account for 21.4% of gram-negative bacterium, respectively. Detection rates of ESBLs in E. coil and K. pneumoniae were 75.0 % （8/12） and 33.3 % （2/6）,respectively. Conclusion Our data may have great significance for the empirical use of antimicrobial agents in the treatment of infections in patients with hematological disease.
出处
《中国基层医药》
CAS
2008年第8期1243-1244,共2页
Chinese Journal of Primary Medicine and Pharmacy
