摘要
目的探讨脑梗死患者急性期血中一氧化氮(NO)、乳酸(LA)与C反应蛋白(CRP)的浓度变化及其临床意义。方法采用可见光分光光度法和速率散射比浊法等测定55例急性脑梗死患者血中NO和LA浓度及CRP的含量,并与40例正常对照者进行比较。结果急性脑梗死患者LA、NO浓度和CRP的含量分别为(85.71±23.34)μmol/L、(1.96±0.95)mmol/L、(10.8±2.11)mg/L,明显高于对照组的(49.26±11.58)μmol/L、(0.89±0.17)mmol/L和(5.65±1.46)mg/L(P<0.05或P<0.01),且三者之间呈明显正相关(r值分别为0.89、0.71和0.78,两两比较P<0.01或P<0.001)。结论NO、LA和CRP均参与急性脑梗死急性期的病理变化过程。
Objective To study the blood level of lactate, nitric oxide and C reactive protein （CRP）, and their relationship in acute cerebral infarction（ACI） patients. Methods Visible spectrophotometry were used to measure the blood levels of LA, NO and CRP. The results acquired from 55 ACI patients were compared with those from 40 patients as normal controls. Results The blood levels of LA, NO and CRP were （85.71±23.34） μmol/L, （1.96± 0.95） mmol/L and （10.8±2.11） mg/L in ACI patients, respectively, and were significantly different from those in the control group （P〈0.05 or P〈0.01 ）. Besides, there is a positive correlation between LA and NO, LA and CRP, and NO and CRP （r were 0.89, 0.71 and 0.78, P〈0.01 or P〈0.001 ）. Conchlsion The results suggested that the measurements of the blood levels of LA, NO and CRP were relatively important at the acute phase of ACI.
出处
《热带医学杂志》
CAS
2008年第9期920-922,共3页
Journal of Tropical Medicine
关键词
急性脑梗死
一氧化氮
乳酸
C反应蛋白
acute cerebral infarction
nitric oxide
lactate
C reactive protein
