期刊文献+

PET/CT显像在宫颈癌原发灶诊断及盆腔淋巴结分期的价值 被引量:9

Role of ^(18)F-FDG PET/CT in diagnosing idiopathy and detecting lymph node metastasis in pelves of cervical cancer
下载PDF
导出
摘要 目的:评价18F-FDG PET/CT显像在诊断宫颈癌原发灶及盆腔淋巴结分期中的临床应用价值。方法:回顾性分析58例患者在手术前PET/CT显像结果,所有恶性肿瘤患者均经手术治疗并行盆腔淋巴结清扫,良性患者经病理及组织学证实,将PET/CT显像结果与病理结果进行对比分析。结果:58例患者中,有28例为宫颈癌,PET/CT显像真阳性24例,真阴性28例,假阴性4例,假阳性2例,与病理结果对比,PET/CT诊断宫颈癌准确率、灵敏度、特异性、阳性预测值和阴性预测值分别为87.9%、85.7%、90%、92.3%、84.3%。28例恶性肿瘤患者,手术共取出盆腔大小不同淋巴结162枚,其中转移淋巴结35枚,与病理和随访结果对比,PET/CT诊断真阳性29枚,假阳性10枚,其诊断的准确率、灵敏度、特异性、阳性预测值和阴性预测值分别为90.1%、82.9%、92.1%;74.4%、95.1%。结论:PET/CT显像对诊断宫颈癌原发灶与盆腔淋巴结转移的准确率高。 Objective:To evaluate the clinical value of PET/CT in judging mediastinal lymph node metastasis in pelves of cervical cancer and determining the diagnosis of cervical cancer. Methods:A retrospective review was performed on 58 patients and all patients were evaluated with PET/CT. 28 of them were cervical cancer. All cervical cancer patients had their pelvic lymph node samples by resection. Each imaging study were evaluated and compared with histopatholegy. Results: For diagnosing the cervical cancer and detecting pelvic lymph metastasis, the rates of accuracy by PET/CT were 87.9% and 90.1% ; sensitivity was 85.7% and 82.9%. Specificity were 90% and92.1%, positive predictive value (PPV) were 92.3% and 74.4%, negative predictive value (NPV) were 84.3% and 95.1%. Conclusion: PET/CT fusion images had high accurate rate in diagnosig cervical cancer and detecting lymph node metastasis in wives of cervical cancer.
出处 《医学影像学杂志》 2008年第9期1052-1054,共3页 Journal of Medical Imaging
关键词 正电子发射断层 体层摄影术 X线计算机 宫颈癌 淋巴 转移 Positron emission tomography X-ray computed Cervical cancer Lymph node,metastasis
  • 相关文献

参考文献5

  • 1Amit A, Beck D, Lowenstein L, et al. The role of hybrid PET/CT in the evaluation of patients with cervical cancer [ J ]. Gynec.ol Oncol, 2006,100:65 - 69. 被引量:1
  • 2Sugawara Y, Eisbruch A, Kosuda S, et al. Evaluation of FDG PET in patients with cervical cancer[J]. J Nud Med,1999,40:1125- 1131. 被引量:1
  • 3Lennan H, Metser U, Grisaru D, et al. Normal and abnormal ^18FFDG endometrial and ovarian uptake in pre-and postmenopansal patients: assessment by PET/CT[J]. J Nucl Med,2004,45:266- 271. 被引量:1
  • 4Rose PG, Adler LP, Rodriguez M, et al. Position emission tomography for evaluating para-aortic nodal metastasis in locally advanced cervical cancer before surgical staging: a surgicopathologic study[J]. J Clin Oncol, 1999,17:41 - 45. 被引量:1
  • 5Reinhardt MJ, Etmtt-Braun C, Vogelgesang D,et al.Metastatic lymph nodes in patients with cervical cancer: detection with MR and FDG PET[ J]. Radiology.2001,218:776 - 782. 被引量:1

同被引文献75

  • 1吴湖炳,王全师,王明芳,王欣璐,郭晓君.呋塞米介入试验在泌尿生殖系统肿瘤^(18)F-FDG PET/CT显像中的应用[J].中华核医学杂志,2005,25(4):206-208. 被引量:23
  • 2朱元方,蔡丽萍,陈桂美,乐爱文,王敏君.MRI在中晚期宫颈癌分期诊断中的价值[J].实用临床医学(江西),2007,8(10):108-111. 被引量:8
  • 3Chung HI-I, Kang KW, Cho JY, et al. Role of magnetic resonance imaging and positron emission tomography/computed tomography in preoperative lymph node detection of uterine cervical cancer[J]. Am J Obstet Gynecol, 2010, 203: 156.el-5. 被引量:1
  • 4Chung HH, Park NH, Kim JW, et al. Role of integrated PET/CT in pelvic lymph node staging of cervical cancer before radical hyster- ectomy[ J]. Gynecol Obstet Invest, 2009, 67: 61-66. 被引量:1
  • 5Sandvik RM, Jensen PT, Hendel HW, et al. Positron emission tomography-computed tomography has a clinical impact for patients with cervical cancer[J]. Dan Med Bull, 2011, 58: A4240. 被引量:1
  • 6Signorelli M, Guerra L, Montanelli L, et al. Preoperative staging of cervical cancer: is 18-FDG-PET/CT really effective in patients with early stage disease[ J] ? Gynecol Oncol, 2011, 123: 236-240. 被引量:1
  • 7Yoo J, Choi JY, Moon SH, et al. Prognostic significance of volume- based metabolic parameters in uterine cervical cancer determined u- sing lSF-fluorodeoxyglucose positron emission tomography[ J]. Int J Gynecol Cancer, 2012, 22: 1226-1233. 被引量:1
  • 8Lee YY, Choi CH, Kim C J, et al. The prognostic significance of the SUVmax( maximum standardized uptake value for F-18 fluorode- oxyglucose) of the cervical tumor in PET imaging for early cervical cancer : preliminary results [ J]. Gynecol Oncol, 2009, 115 : 65-68. 被引量:1
  • 9Crivellaro C, Signorelli M, Guerra L, et al. ISF-FDG PET/CT can predict nodal metastases but not recurrence in early stage uterine cervical cancer[ J]. Gynecol Oncol, 2012, 127: 131-135. 被引量:1
  • 10Kidd EA, E1 Naqa 1, Siegel BA, et al. FDG-PET-based prognostic nomograms for locally advanced cervical cancer[J].Gynecol Oncol, 2012, 127: 136-140. 被引量:1

引证文献9

二级引证文献45

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部