摘要
目的:评价18F-FDG PET/CT显像在诊断宫颈癌原发灶及盆腔淋巴结分期中的临床应用价值。方法:回顾性分析58例患者在手术前PET/CT显像结果,所有恶性肿瘤患者均经手术治疗并行盆腔淋巴结清扫,良性患者经病理及组织学证实,将PET/CT显像结果与病理结果进行对比分析。结果:58例患者中,有28例为宫颈癌,PET/CT显像真阳性24例,真阴性28例,假阴性4例,假阳性2例,与病理结果对比,PET/CT诊断宫颈癌准确率、灵敏度、特异性、阳性预测值和阴性预测值分别为87.9%、85.7%、90%、92.3%、84.3%。28例恶性肿瘤患者,手术共取出盆腔大小不同淋巴结162枚,其中转移淋巴结35枚,与病理和随访结果对比,PET/CT诊断真阳性29枚,假阳性10枚,其诊断的准确率、灵敏度、特异性、阳性预测值和阴性预测值分别为90.1%、82.9%、92.1%;74.4%、95.1%。结论:PET/CT显像对诊断宫颈癌原发灶与盆腔淋巴结转移的准确率高。
Objective:To evaluate the clinical value of PET/CT in judging mediastinal lymph node metastasis in pelves of cervical cancer and determining the diagnosis of cervical cancer. Methods:A retrospective review was performed on 58 patients and all patients were evaluated with PET/CT. 28 of them were cervical cancer. All cervical cancer patients had their pelvic lymph node samples by resection. Each imaging study were evaluated and compared with histopatholegy. Results: For diagnosing the cervical cancer and detecting pelvic lymph metastasis, the rates of accuracy by PET/CT were 87.9% and 90.1% ; sensitivity was 85.7% and 82.9%. Specificity were 90% and92.1%, positive predictive value (PPV) were 92.3% and 74.4%, negative predictive value (NPV) were 84.3% and 95.1%. Conclusion: PET/CT fusion images had high accurate rate in diagnosig cervical cancer and detecting lymph node metastasis in wives of cervical cancer.
出处
《医学影像学杂志》
2008年第9期1052-1054,共3页
Journal of Medical Imaging