摘要
目的研究男性乳腺癌（MBC）的临床特点和可能影响预后的因素。方法回顾1996年1月至2008年1月住院治疗且经病理证实的17例MBC病例，并以同期102例女性乳腺癌患者作对照分析。结果MBC占同期住院治疗的乳腺癌的1．15％（17／1473）。男性组患者的就诊年龄较大、发现肿块至就诊时间较长，就诊时局部皮肤改变及腋窝淋巴结肿大的发生率高于女性组（均P〈0．05），校正了肿瘤分期及腋窝淋巴结状况因素，两组总体5年肿瘤相关生存率差异无统计学意义（P〉0．05）。结论该组MBC患者与女性乳腺癌预后相近，性别不一定是影响MBC的预后因素。
Objective To analyze the clinical data of male breast cancer （MBC）,and investigate the clinical characteristics and factors potentialy affecting prognosis of male breast cancer. Methods A retrospective case-control study was performed on 17 MBC and 102 female breast cancer cases from January 1996 to 2008, treated in the hospital with pathologic proofs. Results MBC accounted for 1.15% （17/1473） of all cases. The initial visiting age was older, the time from the appearance of lump to the first doctor contact was longer, the positive rate of axillary lymph node metastasis and local skin change incidence ratio was higher in the male group （P 〈0.05）; there was no significant difference about overall 5-year disease-specific survival between the two groups （P 〉0.05）, when tumor stages and nodal involvement were checked. Conclusion This study suggests that the two groups prognosis is similar, the gender is uncertain prognostic factor.
出处
《肿瘤研究与临床》
CAS
2008年第9期597-599,共3页
Cancer Research and Clinic
关键词
乳腺肿瘤
男性
病例对照研究
Breast neoplasms, male
Case-Control study
