摘要
目的了解海产品对妇女尿碘水平的影响，为寻求其他的适宜补碘途径提供依据。方法2006年在新疆伊宁县妇幼保健院，选择参加体检的孕妇和非孕妇女，年龄20～40岁，记录食入海产品的种类及食入频次，采集日间随意尿样和家庭食用盐。尿碘测定采用砷铈分光光度法，盐碘测定采用直接滴定法。结果共调查了198位妇女，其中孕妇148人，非孕妇50人，尿碘中位数为87．5μg／L。在基本不食用、很少食用、经常食用海产品的妇女中，尿碘中位数分别为83.49、91．52、166．45μg／L，组间比较差异有统计学意义（Х^2=6．202，P〈0．05）。食用海产品的非孕妇尿碘中位数（90．94μg/L）高于孕妇（84．79μg／L），二者比较差异有统计学意义（U=3318．00，P〈0．05）。在孕妇中，很少食用海产品的妇女尿碘中位数（94．46μg/L）与基本不食用海产品的妇女（83．28μg／L）比较，差异有统计学意义（U=1257．5，P〈0．05）；在孕晚期，基本不食用、很少食用、经常食用海产品妇女尿碘中位数分别为81．93、97．97、140．18μg/L，组间比较差异有统计学意义（Х^2=6．80，P〈0．05）。结论孕妇每周食入一定量的海产品，就可使尿碘水平得到相应提高，食人频次越多，尿碘水平也相应越高，建议在碘盐推广困难的地区，对孕妇多进行食用海产品的宣传．减少克汀病患儿的出生。
Objective To investigate the effect of seafood intake on the urinary iodine level in women for exploring an alternative to iodine supplementation. Methods Healthy pregnant women and non-pregnant women, aged 20 - 40 years, were selected during their health examination in local women＇s health care in 2006. The types of seafood and its intake frequency were recorded from these women, and urine and kitchen salt samples were collected for iodine determination. Results A total of 198 women including 148 pregnant and 50 non-pregnant women were recruited for this study; they had a median level of urine iodine of 87.51 μg/L. The median levels of urine iodine of 83.49,91.52,166.45 μg/L in three group women classified as hardly, seldom and often intake of see food showed significant difference （Х^2 = 6.202 ,P 〈 0.05）. Urine iodine level in non-pregnant women taking seafood （90.94 μg/L） was higher than that in pregnant women（84.79 μg/L）, the difference being statistically significant （U = 3318.00, P 〈 0.05）. The urine iodine in pregnant women with seldom intake of seafood （94.46 μg/L） was significantly higher than that in the hardly intake women（83.28 μg/L）, the difference being statistically significant （U = 1257.5, P 〈 0.05）. During late period of gestation, the urinary iodine in the women of three status of hardly, seldom and often intake of seafood were 81.93,97.97 and 140.18 μg/L, respective, with significant differences among them. Conclusions A certain amount of seafood taken every week can increase urine iodine levels, and a direct relationship was observed. Therefore, we suggest that it is necessary to advocate taking seafood to pregnant women for prevention of cretinism, particularly in the areas where iodized salt was difficult to implement.
出处
《中国地方病学杂志》
CAS
CSCD
北大核心
2008年第5期535-537,共3页
Chinese Jouranl of Endemiology
基金
卫生部科学研究基金项目（2005-01）.志谢 参与本次调查和检测工作的还有：新疆伊犁哈萨克自治州疾病预防控制中心沙达拜·阿布都热合曼、亚德卡尔·吐尔逊、刘冬,新疆乌鲁木齐市疾病预防控制中心刘毅、马俊杰,天津医科大学内分泌研究所张璐、叶艳、董金茹
新疆疾病预防控制中心刘万里同志帮助完成统计分析.在此一并感谢
关键词
碘
缺乏症
妇女
海产品
Iodine
Deficiency diseases
Women
Sea food
