摘要
目的探讨多发性硬化首发症状多项因素与预后的关系。方法通过回顾性分析三家医院近十年来临床诊治的82例多发性硬化患者的首发症状,研究其首发症状在良、恶性MS中的发生率,采用连续校正卡方检验和t检验,对以上数据进行统计显示与预后的关系。结果以运动障碍、共济失调、括约肌障碍为首发症状的多发性硬化患者发生恶性MS可能性较良性MS明显增大,年龄大于40岁及男性患者,也是恶性MS高危因素,预后较差;以视觉障碍、感觉障碍为首发症状的多发性硬化患者发生良性MS可能性较大,预后较好。认知障碍、癫痫等为首发症状者无差异。结论本项研究表明,多发性硬化不同的首发症状及年龄、性别等多项因素可以提示其预后。
Objective To analyze relation between multiple sclerosis prognosis and its symptoms at onset. Methods Based on retrospective observation we take 82 patients with multiple sclerosis to analyze the relation between multiple sclerosis prognosis and its symptoms at onset. Results Multiple sclerosis with symptoms of sensory,optic impairment at onset are more likely to indicate a relatively favorable course, female sex, early age at onset are also conversely, symptoms of dyskinesia, ataxia, sphincter disturbance at onset mean bad prognosis. Conclusion Symptoms at onset of multiple sclerosis are capable to hint prognosis.
出处
《医药论坛杂志》
2008年第17期5-6,共2页
Journal of Medical Forum
关键词
多发性硬化
首发症状
预后
Multiple sclerosis
Symptoms at onset
Prognosis
