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181例小儿下呼吸道疾病患者病原菌分布及耐药性研究 被引量:7

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摘要 目的:分析小儿内科下呼吸道疾病病原菌的分布及药敏试验结果,探讨用药对策。方法:对181例小儿内科下呼吸道疾病患者的痰标本和血标本进行细菌培养并作药敏试验。结果:181例下呼吸道疾病患儿的病原学送检率达81.2%。147例标本中检出88株病原菌,阳性率48.6%。病原菌前4位依次为肺炎支原体(48.9%)、肺炎链球菌(13.6%)、流感嗜血杆菌(12.5%)和肺炎克雷伯菌(6.8%)。革兰阴性杆菌32例(36.4%),革兰阳性球菌13例(14.8%),真菌3例(3.4%)。革兰阴性杆菌较敏感药物分别为阿莫西林/克拉维酸、哌拉西林/他唑巴坦、头孢呋辛、亚胺培南/西司他丁、美罗培南、阿米卡星、环丙沙星。肺炎链球菌耐药形势严峻,较敏感药物依次为万古霉素、左氧氟沙星和阿莫西林。结论:我院小儿下呼吸道疾病标本送检率高于卫生部规定的70%,病原菌的构成与文献报道基本相符,细菌耐药形势严峻。
机构地区 烟台毓璜顶医院
出处 《中国医院药学杂志》 CAS CSCD 北大核心 2008年第16期1411-1412,共2页 Chinese Journal of Hospital Pharmacy
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  • 1Bartlett JG, Breiman RF, Mandell LA, et al. Community-acquired pneumonia in adults:guidelines for management.The Infectious Diseases Society of America[J]. Clin Infect Dis,1998 ,26:811-838. 被引量:1
  • 2Lieberman D,Schlaeffer F,Boldur I,et al. Multiple pathogens in adult patients admitted with community-acquired pneumonia: a one year prospective study of 346 consecutive patients[J]. Thorox, 1996 , 51:179-184. 被引量:1
  • 3Ruiz-Gonzalez A,Falguera M,Nogues A,et al. Is Streptococcus pneumoniae the leading cause of pneumonia of unknown etiology? A microbiologic study of lung aspirates in consecutive patients with community-acquired pneumonia[J]. Am J Med,1999,106:385-390. 被引量:1
  • 4Moola S,Hagberg L,Churchyard GA,et al. A multicenter study of grepafloxacin and clarithromycin in the treatment of patients with community-acquired pneumonia[J]. Chest,1999, 116:974-983. 被引量:1
  • 5Antela A,Guerrero A,Meseguer M,et al.Community-acquired pneumonia:prospective study of 101 adult,immunocompetent patients for 1 year[J]. Enferm Infect Microbiol Clin, 1993 ,11:525-530. 被引量:1
  • 6Thornsberry C,Jones ME, Hickey ML, et al. Resistance surveillance of Streptococcus pneumoniae, Haemophilus influenzae and Moraxella catarrhalis isolated in the United States, 1997-1998[J]. J Antimicrob Chemother, 1999,44:749-759. 被引量:1
  • 7Sahm DF, Karlowsky JA, Kelly LJ, et al. Need for annual surveillance of antimicrobial resistance in Streptococcus pneumoniae in the United States: 2-Year longitudinal analysis[J]. Antimicrob Agents Chemother,2001,45:1037-1042. 被引量:1
  • 8Ramphal R, Bille J, Yigit H,et al.Outcomes of infections caused by extended spectrum beta-lactamase(ESBL) producing strains of E.coli and Klebsiella spp.treated with cefepime[R].2002,12th European Congress of Clinial Microbiology and Infectious Disease. 被引量:1
  • 9陈迁,王睿,方向群,刘又宁.盐酸氟罗沙星对铜绿假单胞菌生物被膜的影响[J].中国抗生素杂志,1997,22(6):435-441. 被引量:14
  • 10方向群,刘又宁,陈迁,王睿.阿奇霉素对生物被膜的抑制及对氟罗沙星的增效作用[J].中华结核和呼吸杂志,1998,21(9):538-540. 被引量:67

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