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幽门螺杆菌相关性消化性溃疡根除幽门螺杆菌治疗的疗程研究 被引量:15

Research of the treatment to eradicate helicobacter pylori associated peptic ulcer
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摘要 目的:观察幽门螺杆菌(HP)相关性消化性溃疡(胃/十二指肠溃疡)根除HP治疗的常用三联治疗方案7d疗程和14d疗程的疗效和安全性。方法:将60例HP检测(尿素酶法)阳性的消化性溃疡患者随机分为A组和B组各30例,A组治疗7d,B组治疗14d,观察HP根除情况,溃疡愈合情况以及不良反应。结果:临床总有效率B组明显优于A组(P<0.01)。结论:14d疗程明显优于7d疗程,药物不良反应无明显增加。 Objective:To observe the efficacy and safety of the commonly used triple therapy program for 7 days' cure and 14 days' cure to eradicate helicobacter pylori associated peptic ulcer Methods:First divide 60 cases detected HP (urea enzymatic) positive peptic ulcer patients randomly into Group A and Group B (each with 30 cases).Group A was given the treatment of 7 days and group B of 14 days. Then observe the eradication of Helicobacter Pylori ,ulcer conglutination,and side effect. Results:The total effective rate was significantly higher in group B than in group A (P〈0.01). Conclusion:The 14 days' cure were obviously better than the 7 days' cure, no significant increase of drug adverse reactions.
出处 《中国医药导报》 CAS 2008年第26期50-51,共2页 China Medical Herald
关键词 幽门螺杆菌 消化性溃疡 疗程 Helicobacter Pylori Peptic ulcer cure
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