期刊文献+

糖尿病合并非酒精性脂肪性肝病的治疗进展 被引量:1

Advances in treatment of nonalcoholic fatty liver disease complicated with diabetes
下载PDF
导出
摘要 随着生活水平的提高和生活方式的改变,糖尿病合并非酒精性脂肪性肝病(NAFLD)的发病率不断升高。虽有多种方法治疗糖尿病合并NAFLD,如生活方式的改变、增加胰岛素敏感性、抗氧化、调节血脂紊乱以及对一些风险因素的防治等,但由于其病因和发病机制尚未完全明了,仍缺乏更为有效的治疗方法。本文就近年来对糖尿病合并NAFLD的治疗进展作一综述。 With living standard improving and lifestyle changing for the past few years, the incidence of nonal-coholic fatty liver disease (NAFLD)with diabetes has increased unceasingly. There are many kinds of therapy methods for NAFLD with diabetes fatty, such as changing lifestyle, increasing insulin sensitivity, antioxidation, regulating blood fat disorder and individual precaution and treatment for other risk fators. But because it's etiological and pathogenesis have not been elucidated completely, the effective therapy of NAFLD has not been found . This article reviews the therapy for NAFLD with diabetes in recent years.
作者 郭琳 杨静
出处 《国际内科学杂志》 CAS 2008年第8期460-463,472,共5页 International Journal of Internal Medicine
关键词 非酒精性脂肪性肝病 胰岛素抵抗 氧化应激 糖尿病 脂肪变性 Nonalcoholic fatty liver disease Insulin resistance Oxidative stress Diabetes mellitus Therapy
  • 相关文献

参考文献30

  • 1Calamita G, Portincasa P. Present and future therapeutic strategies in non-alcoholic fatty liver disease. Expert Opin Ther Targets ,2007,11 ( 9 ) : 1231-1249. 被引量:1
  • 2Abdelmalek MF, Diehl AM. Nonalcoholic fatty liver disease as a complication of insulin resistance. Med Clin North Am, 2007,91 (6) : 1125-1149. 被引量:1
  • 3Adams LA, Angulo P. Treatment of non-alcoholic fatty liver disease. Postgrad Med J, 2006,82(967) :315-322. 被引量:1
  • 4Nugent C, Younossi ZM. Evaluation and management of obesity-related nonalcoholic fatty liver disease. Nat Clin Pract Gastroenterol Hepatol, 2007,4 ( 8 ) :432441. 被引量:1
  • 5Duvnjak M, Lerotic I, Barsic N, et al. Pathogenesis and management issues for non-alcoholic fatty liver disease. World J Gastroenterol, 13 (34) :4539 4550. 被引量:1
  • 6Zivkovic AM, German JB, Sanyal AJ. Comparative review of diets for the metabolic syndrome: implications for nonalcoholic fatty liver disease . Am J Clin Nutr, 86 ( 2 ) : 285- 300. 被引量:1
  • 7Salmenniemi U, Ruotsalainen E, Pihlajamaki J, et al. Multiple abnormalities in glucose and energy metabolism and coordinated changes in levels of adiponectin, cytokines, and adhesion molecules in subjects with metabolic syndrome. Circulation, 2004,110 (25) : 3842-3848. 被引量:1
  • 8Donnelly KL, Smith CI, Schwarzenberg SJ, et al. Sources of fatty acids stored in liver and secreted via lipoproteins in patients with nonalcoholic fatty liver disease. J Clin Invest, 2005,115 (5) : 1343-1351. 被引量:1
  • 9Wang D, Wei Y, Pagliassotti MJ. Saturated fatty acids promote endoplasmic reticulum stress and liver injury in rats with hepatic steatosis. Endocrinology, 2006, 147 ( 2 ) : 943- 951. 被引量:1
  • 10Musso G, Gambino R, De Michieli F, et al. Dietaryhabits and their relations to insulin resistance and postprandial lipemia in nonalcoholic steatohepatitis. Hepatology, 2003, 37(4) :909 -916. 被引量:1

同被引文献9

引证文献1

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部