摘要
目的:探讨血浆sCD40L含量评价溃疡性结肠炎(UC)病情活动性与严重性的意义。方法:采用ELISA法检测38例活动期UC患者、15例缓解期UC者及30例健康对照者的血浆sCD40L、C反应蛋白(CRP)含量,评价病情轻重程度。结果:活动期患者组血CRP含量、血浆sCD40L含量显著高于缓解与对照组(P<0.05),且两者与UC病情活动性、病情分型均呈显著正相关,两者本身也存在正相关。结论:血浆sCD40L含量可作为评价UC患者病情活性及严重程度的良好指标。
Objective： To investigate the expression of sCD40L in the patients with ulcerative colitis （UC）, and analyze its clinical significance. Methods：The expression serum of sCD40L was assessed by ELISA in the patients with 15 remission cases, 38 active stage cases and 30 control cases. Results： The serum levels of sCD40L and CRP in active stage cases were significantly higher than those in paracmasia group and control group （P〈0.05）, and both were significant positive correlation with the reactiveness and typing of pathogenetic condition in UC. Conclusion： The level of sCD40L is related to the reactiveness and sever- ity of pathogenetic condition in patients with ulcerative colitis.
出处
《中国临床医学》
北大核心
2008年第4期503-504,共2页
Chinese Journal of Clinical Medicine
