摘要
对细叶草乌(Aconitum macrorhynchum)中的二萜生物碱进行研究。利用反复硅胶柱层析、重结晶等分离方法从中分离得到了5个二萜生物碱,用有机波谱学和理化常数测定鉴定了其结构,分别是:查斯曼宁(chas-manine,1)、塔拉萨敏(talatisamine,2)、滇乌碱(yunaconitine,3)、印乌碱(indaconoitine,4)、粗茎乌碱甲(crassi-cauline A,5)、同时还得到β-谷甾醇(β-sitosterol,6)和β-胡萝卜苷(β-daucosterol,7)。以上化合物均为首次从该植物中分离得到。
Five diterpenoid alkaloids were isolated from the ethanol extracts of the root of Aconitum macrorhynchum by repeated gel and silica gel column chromatogramphy. On the basis of direct comparison with authentic samples and literature data, they were determined as chasmanine （ 1 ）, talatisamine （ 2）, yunaconitine （ 3 ）, indaconitine （4）, and crassicauline A （5）. These compounds were isolated from the plant for the first time.
出处
《天然产物研究与开发》
CAS
CSCD
2008年第4期636-638,共3页
Natural Product Research and Development
基金
云南省自然科学基金(2005B0001Q)
云南大学自然科学基金(2003Q010A)
关键词
细叶草乌
化学成分
二萜生物碱
Aconitum macrorhynchum
chemical constituents
diterpenoid alkaloids
